Abstract
Abnormal zinc homeostasis is involved in β-amyloid (Aβ) plaque formation and, therefore, the zinc load is a contributing factor in Alzheimer's disease (AD). However, the involvement of zinc in amyloid precursor protein (APP) processing and Aβ deposition has not been well established in AD animal models in vivo.
Originalsprog | Engelsk |
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Tidsskrift | P L o S One |
Vol/bind | 5 |
Nummer | 12 |
Sider (fra-til) | e15349 |
ISSN | 1932-6203 |
DOI | |
Status | Udgivet - 1 jan. 2010 |