Vulvær intraepithelial neoplasi

Signe Østergaard Hansen, Christina Steen Vorbeck, Mette Meinert

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelFormidling

Abstract

Vulvar intraepithelial neoplasia
Vulvar intraepithelial neoplasia (VIN) is a rare but premalig­nant condition. VIN has two aetiological pathways: a human papillomavirus (HPV)-dependent pathway, which is a vulvar high-grade squamous intraepithelial lesion (HSIL), and an HPV-independent pathway, called differentiated VIN (d-VIN), associated with lichen sclerosus. d-VIN is more aggressive than vulvar HSIL. In case of symptoms, a biopsy should be performed. The recurrence risk is high: 25-50% regardless of treatment type. We recommend treatment with imiquimod as first choice to avoid mutilating surgery. Particular attention must be payed to immunosuppressed patients with VIN. HPV-vaccine can be discussed with patients with vulvar HSIL.
OriginalsprogDansk
ArtikelnummerV2170931
TidsskriftUgeskrift for Læger
Vol/bind2018
Nummer180
Sider (fra-til)2-5
Antal sider4
ISSN0041-5782
StatusUdgivet - 1 maj 2018

Emneord

  • Vulvar Neoplasms
  • imiquimod
  • vulva dysplasi imiquimod

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