Validation of the semi-structured Psychotic Depression Assessment Scale (PDAS) interview

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Objective: Recently, a semi-structured interview dedicated to aid rating on the Psychotic Depression Assessment Scale (PDAS) was developed. Here, we aimed to validate PDAS ratings collected via this semi-structured interview. Methods: A total of 50 patients with psychotic depression - 34 with unipolar psychotic depression and 16 with bipolar psychotic depression - were recruited for the study. The following aspects of validity were investigated: clinical validity, psychometric validity (scalability), and responsiveness. Results: The PDAS ratings were clinically valid (Spearman's coefficient of correlation between PDAS total scores and Clinical Global Impressions scale - severity of illness ratings=0.66, p<0.001), scalable (Loevinger's coefficient of heterogeneity at endpoint=0.45), and responsive (no participants met the criterion for remission on the PDAS (total score <8) at baseline - at endpoint 74% (95% CI: 60-85) of the participants met this criterion). Conclusions: The semi-structured PDAS interview provides valid ratings of the severity of psychotic depression.

TidsskriftActa Neuropsychiatrica
Sider (fra-til)175-180
Antal sider6
StatusUdgivet - 1 jun. 2018

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