Aarhus Universitets segl

English

Du er her: AU » Om AU » Organisation » Use of antibiotics is associated with lower enterolactone...

Om AU

Use of antibiotics is associated with lower enterolactone plasma concentration

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

Standard

Use of antibiotics is associated with lower enterolactone plasma concentration. / Bolvig, Anne Katrine; Kyrø, Cecilie; Nørskov, Natalja et al.
I: Molecular Nutrition & Food Research, Bind 60, Nr. 12, 12.2016, s. 2712-2721.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

Harvard

Bolvig, AK, Kyrø, C, Nørskov, N, Eriksen, AK, Christensen, J, Tjønneland, A, Knudsen, KEB & Olsen, AV 2016, 'Use of antibiotics is associated with lower enterolactone plasma concentration', Molecular Nutrition & Food Research, bind 60, nr. 12, s. 2712-2721. https://doi.org/10.1002/mnfr.201600566

APA

Bolvig, A. K., Kyrø, C., Nørskov, N., Eriksen, A. K., Christensen, J., Tjønneland, A., Knudsen, K. E. B., & Olsen, A. V. (2016). Use of antibiotics is associated with lower enterolactone plasma concentration. Molecular Nutrition & Food Research, 60(12), 2712-2721. https://doi.org/10.1002/mnfr.201600566

CBE

Bolvig AK, Kyrø C, Nørskov N, Eriksen AK, Christensen J, Tjønneland A, Knudsen KEB, Olsen AV. 2016. Use of antibiotics is associated with lower enterolactone plasma concentration. Molecular Nutrition & Food Research. 60(12):2712-2721. https://doi.org/10.1002/mnfr.201600566

MLA

Bolvig, Anne Katrine et al. "Use of antibiotics is associated with lower enterolactone plasma concentration". Molecular Nutrition & Food Research. 2016, 60(12). 2712-2721. https://doi.org/10.1002/mnfr.201600566

Vancouver

Bolvig AK, Kyrø C, Nørskov N, Eriksen AK, Christensen J, Tjønneland A et al. Use of antibiotics is associated with lower enterolactone plasma concentration. Molecular Nutrition & Food Research. 2016 dec.;60(12):2712-2721. doi: 10.1002/mnfr.201600566

Author

Bolvig, Anne Katrine ; Kyrø, Cecilie ; Nørskov, Natalja et al. / Use of antibiotics is associated with lower enterolactone plasma concentration. I: Molecular Nutrition & Food Research. 2016 ; Bind 60, Nr. 12. s. 2712-2721.

Bibtex

@article{5004bbebc95f403ea0273941eea5d2ff,
title = "Use of antibiotics is associated with lower enterolactone plasma concentration",
abstract = "Scope High enterolactone levels may have health benefits in relation to risk of noncommunicable diseases. Enterolactone is produced by the colonic microbiota after intake of lignans and treatment with antimicrobials may result in altered enterolactone production. This study investigates the association between antibiotic use and enterolactone concentration. Methods and results Using LC–MS/MS, enterolactone concentrations were quantified in plasma samples from 2237 participants from the Diet, Cancer and Health cohort. The participants were healthy at enrollment, but were later diagnosed with cancer. At enrollment, participants had blood drawn and completed a food frequency questionnaire and lifestyle questionnaire. Antibiotic use was assessed as reimbursed antibiotic prescriptions up to 12 months before enrollment. Antibiotic use ≤3 months before enrollment was associated with a 41% (Δcrude: –41; 95% CI: –52, –28) lower enterolactone concentration in women and 12% in men (Δcrude: –12; 95% CI: –31, 11), while antibiotic use >3–12 months before enrollment was associated with 26% lower enterolactone in women (Δcrude: –26; 95% CI: –37, –14) and 14% in men (Δcrude: –14; 95% CI: –28, 1). Conclusion Use of antibiotics up to 12 months before enrollment was associated with lower plasma enterolactone levels, especially among women.",
keywords = "antibiotics, enterolactone, epidemiology, lignans, microbiota",
author = "Bolvig, {Anne Katrine} and Cecilie Kyr{\o} and Natalja N{\o}rskov and Eriksen, {Anne Kirstine} and Jane Christensen and Anne Tj{\o}nneland and Knudsen, {Knud Erik Bach} and Olsen, {Anja Viendahl}",
year = "2016",
month = dec,
doi = "10.1002/mnfr.201600566",
language = "English",
volume = "60",
pages = "2712--2721",
journal = "Molecular Nutrition & Food Research",
issn = "1613-4125",
publisher = "Wiley-VCH Verlag",
number = "12",

}

RIS

TY - JOUR

T1 - Use of antibiotics is associated with lower enterolactone plasma concentration

AU - Bolvig, Anne Katrine

AU - Kyrø, Cecilie

AU - Nørskov, Natalja

AU - Eriksen, Anne Kirstine

AU - Christensen, Jane

AU - Tjønneland, Anne

AU - Knudsen, Knud Erik Bach

AU - Olsen, Anja Viendahl

PY - 2016/12

Y1 - 2016/12

N2 - Scope High enterolactone levels may have health benefits in relation to risk of noncommunicable diseases. Enterolactone is produced by the colonic microbiota after intake of lignans and treatment with antimicrobials may result in altered enterolactone production. This study investigates the association between antibiotic use and enterolactone concentration. Methods and results Using LC–MS/MS, enterolactone concentrations were quantified in plasma samples from 2237 participants from the Diet, Cancer and Health cohort. The participants were healthy at enrollment, but were later diagnosed with cancer. At enrollment, participants had blood drawn and completed a food frequency questionnaire and lifestyle questionnaire. Antibiotic use was assessed as reimbursed antibiotic prescriptions up to 12 months before enrollment. Antibiotic use ≤3 months before enrollment was associated with a 41% (Δcrude: –41; 95% CI: –52, –28) lower enterolactone concentration in women and 12% in men (Δcrude: –12; 95% CI: –31, 11), while antibiotic use >3–12 months before enrollment was associated with 26% lower enterolactone in women (Δcrude: –26; 95% CI: –37, –14) and 14% in men (Δcrude: –14; 95% CI: –28, 1). Conclusion Use of antibiotics up to 12 months before enrollment was associated with lower plasma enterolactone levels, especially among women.

AB - Scope High enterolactone levels may have health benefits in relation to risk of noncommunicable diseases. Enterolactone is produced by the colonic microbiota after intake of lignans and treatment with antimicrobials may result in altered enterolactone production. This study investigates the association between antibiotic use and enterolactone concentration. Methods and results Using LC–MS/MS, enterolactone concentrations were quantified in plasma samples from 2237 participants from the Diet, Cancer and Health cohort. The participants were healthy at enrollment, but were later diagnosed with cancer. At enrollment, participants had blood drawn and completed a food frequency questionnaire and lifestyle questionnaire. Antibiotic use was assessed as reimbursed antibiotic prescriptions up to 12 months before enrollment. Antibiotic use ≤3 months before enrollment was associated with a 41% (Δcrude: –41; 95% CI: –52, –28) lower enterolactone concentration in women and 12% in men (Δcrude: –12; 95% CI: –31, 11), while antibiotic use >3–12 months before enrollment was associated with 26% lower enterolactone in women (Δcrude: –26; 95% CI: –37, –14) and 14% in men (Δcrude: –14; 95% CI: –28, 1). Conclusion Use of antibiotics up to 12 months before enrollment was associated with lower plasma enterolactone levels, especially among women.

KW - antibiotics

KW - enterolactone

KW - epidemiology

KW - lignans

KW - microbiota

U2 - 10.1002/mnfr.201600566

DO - 10.1002/mnfr.201600566

M3 - Journal article

C2 - 27500753

VL - 60

SP - 2712

EP - 2721

JO - Molecular Nutrition & Food Research

JF - Molecular Nutrition & Food Research

SN - 1613-4125

IS - 12

ER -