Up, down, and around: Identifying recurrent interactions within and between super-secondary structures in β-propellers

Søren Skou Thirup, Vikas Gupta, Esben Meldgaard Høgh Quistgaard

Publikation: Bidrag til bog/antologi/rapport/proceedingBidrag til bog/antologiForskningpeer review

Abstract

The examination and analysis of super-secondary structures or other speci fi c structural patterns associated with particular functions, sequence motifs, or structural contexts require that the set of structures examined shares the same feature. This seems obvious but in practice this may often present problems such as identifying complete sets of data avoiding false positives. In the case of the β -propeller structures the symmetry of the propeller creates problems for many structure similarity search programs. Here we present a procedure that will identify propeller structures in PDB and assign them to the different N-propeller types. In addition we outline methods to examine similarities and differences within and between the four stranded up-and-down blades of the β-propeller.

OriginalsprogEngelsk
TitelProtein Supersecondary Structures
RedaktørerAlexander E Kister
Antal sider16
ForlagHumana Press
Publikationsdato2012
Sider35-50
Kapitel3
ISBN (Trykt)978-1-62703-064-9
ISBN (Elektronisk)978-1-62703-065-6
DOI
StatusUdgivet - 2012
NavnMethods in Molecular Biology
Vol/bind932
ISSN1064-3745

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