TRACE: An Unbiased Method to Permanently Tag Transiently Activated Inputs

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TRACE : An Unbiased Method to Permanently Tag Transiently Activated Inputs. / Krauth, Nathalie; Khalil, Valentina; Jariwala, Meet; Mermet-Joret, Noemie; Vestergaard, Anne Katrine; Capogna, Marco; Nabavi, Sadegh.

I: Frontiers in Cellular Neuroscience, Bind 14, 114, 05.2020.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

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@article{b2493c4d0fae4b97a27fbc706cb38f1c,
title = "TRACE: An Unbiased Method to Permanently Tag Transiently Activated Inputs",
abstract = "A fundamental interest in circuit analysis is to parse out the synaptic inputs underlying a behavioral experience. Toward this aim, we have devised an unbiased strategy that specifically labels the afferent inputs that are activated by a defined stimulus in an activity-dependent manner. We validated this strategy in four brain circuits receiving known sensory inputs. This strategy, as demonstrated here, accurately identifies these inputs.",
keywords = "innate fear, mouse behavior, neural circuits, optogenetics, viral tracing",
author = "Nathalie Krauth and Valentina Khalil and Meet Jariwala and Noemie Mermet-Joret and Vestergaard, {Anne Katrine} and Marco Capogna and Sadegh Nabavi",
year = "2020",
month = may,
doi = "10.3389/fncel.2020.00114",
language = "English",
volume = "14",
journal = "Frontiers in Cellular Neuroscience",
issn = "1662-5102",
publisher = "Frontiers Media S.A",

}

RIS

TY - JOUR

T1 - TRACE

T2 - An Unbiased Method to Permanently Tag Transiently Activated Inputs

AU - Krauth, Nathalie

AU - Khalil, Valentina

AU - Jariwala, Meet

AU - Mermet-Joret, Noemie

AU - Vestergaard, Anne Katrine

AU - Capogna, Marco

AU - Nabavi, Sadegh

PY - 2020/5

Y1 - 2020/5

N2 - A fundamental interest in circuit analysis is to parse out the synaptic inputs underlying a behavioral experience. Toward this aim, we have devised an unbiased strategy that specifically labels the afferent inputs that are activated by a defined stimulus in an activity-dependent manner. We validated this strategy in four brain circuits receiving known sensory inputs. This strategy, as demonstrated here, accurately identifies these inputs.

AB - A fundamental interest in circuit analysis is to parse out the synaptic inputs underlying a behavioral experience. Toward this aim, we have devised an unbiased strategy that specifically labels the afferent inputs that are activated by a defined stimulus in an activity-dependent manner. We validated this strategy in four brain circuits receiving known sensory inputs. This strategy, as demonstrated here, accurately identifies these inputs.

KW - innate fear

KW - mouse behavior

KW - neural circuits

KW - optogenetics

KW - viral tracing

UR - http://www.scopus.com/inward/record.url?scp=85085733649&partnerID=8YFLogxK

U2 - 10.3389/fncel.2020.00114

DO - 10.3389/fncel.2020.00114

M3 - Journal article

C2 - 32499680

AN - SCOPUS:85085733649

VL - 14

JO - Frontiers in Cellular Neuroscience

JF - Frontiers in Cellular Neuroscience

SN - 1662-5102

M1 - 114

ER -