Three-dimensional dosimetry of dose degradations around gold markers in spot-scanning proton therapy

TY - GEN

T1 - Three-dimensional dosimetry of dose degradations around gold markers in spot-scanning proton therapy

AU - Valdetaro, Lia B.

AU - Stolarczyk, Liliana

AU - Skyt, Peter S.

AU - Petersen, Stine E.

AU - Rønde, Heidi S.

AU - Balling, Peter

AU - Petersen, Jørgen B.B.

AU - Muren, Ludvig P.

N1 - Publisher Copyright: © Published under licence by IOP Publishing Ltd.

PY - 2024

Y1 - 2024

N2 - Fiducial markers are necessary for some tumor sites to ensure safe and accurate delivery of radiotherapy including proton therapy (PT). However, the high metal content of the markers may lead to shadowing of the proton beam. The aim of this study was to investigate the dose degradations around three fiducial marker types implanted in different configurations into a 3D dosimeter. The dosimeters were irradiated with a clinically relevant prostate cancer PT plan. Gamma comparisons (2%-2mm) between the control (no marker) and marker dosimeters resulted in a pass rate of 97%, and no significant differences were observed in the isodoses, indicating that markers did not affect dose coverage to the target. However, due to optical artifacts, the 3D dosimeter was unable to resolve the regions within a few millimeters from the markers.

AB - Fiducial markers are necessary for some tumor sites to ensure safe and accurate delivery of radiotherapy including proton therapy (PT). However, the high metal content of the markers may lead to shadowing of the proton beam. The aim of this study was to investigate the dose degradations around three fiducial marker types implanted in different configurations into a 3D dosimeter. The dosimeters were irradiated with a clinically relevant prostate cancer PT plan. Gamma comparisons (2%-2mm) between the control (no marker) and marker dosimeters resulted in a pass rate of 97%, and no significant differences were observed in the isodoses, indicating that markers did not affect dose coverage to the target. However, due to optical artifacts, the 3D dosimeter was unable to resolve the regions within a few millimeters from the markers.

UR - http://www.scopus.com/inward/record.url?scp=85199263425&partnerID=8YFLogxK

U2 - 10.1088/1742-6596/2799/1/012019

DO - 10.1088/1742-6596/2799/1/012019

M3 - Conference article

AN - SCOPUS:85199263425

SN - 1742-6596

VL - 2799

JO - Journal of Physics: Conference Series

JF - Journal of Physics: Conference Series

IS - 1

M1 - 012019

T2 - 13th International Conference on 3D Dosimetry, IC3DDose 2024

Y2 - 17 June 2024 through 19 June 2024

ER -