Three birds with one stone: a protocol for a randomised intervention study to increase participation in cervical and colorectal cancer screening among women attending breast cancer screening

TY - JOUR

T1 - Three birds with one stone

T2 - a protocol for a randomised intervention study to increase participation in cervical and colorectal cancer screening among women attending breast cancer screening

AU - Helgestad, Anne Dorte Lerche

AU - Larsen, Mette Bach

AU - Njor, Sisse

AU - Tranberg, Mette

AU - Petersen, Lone Kjeld

AU - Andersen, Berit

N1 - © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

PY - 2022/9/22

Y1 - 2022/9/22

N2 - INTRODUCTION: The participation rate is higher in breast cancer screening than in cervical cancer (CCU) and colorectal cancer (CRC) screening. In this cluster-randomised study, we aim to evaluate an intervention offering home-based CCU and CRC screening to women when attending breast cancer screening if they are overdue for CCU and/or CRC screening.METHODS AND ANALYSIS: On intervention days, one of the five breast cancer screening units in the Central Denmark Region will be randomly allocated to intervention, whereas the remaining units will serve as control. Women attending breast cancer screening in the intervention unit will be offered information regarding their CCU and CRC screening history, and, if overdue, they will be offered self-sampling screening kits. For CCU screening, women aged 50-64 years will be offered a vaginal self-sampling kit for human papillomavirus testing. For CRC screening, women aged 50-69 years will be offered a kit to obtain a faecal immunochemical test. Women attending the control units will receive only standard care.After the intervention, a survey will be sent to all women in the intervention and control group, asking about their experience while attending breast cancer screening.Primary outcomes will be difference in the coverage in CCU and CRC screening 6 months after intervention between the intervention and the control group, and difference in participation rates 6 months after intervention for those who were overdue for CCU and/or CRC screening at the time of the intervention.ETHICS AND DISSEMINATION: The project is listed in the record of processing activities for research projects in the Central Denmark Region (R. No.: 1-16-02-217-21). According to the Danish Consolidation Act on Research Ethics Review of Health Research Project, this study was not notifiable to the Committee (R. No.: 1-10-72-1-21). The findings will be disseminated in peer-reviewed scientific journals.TRIAL REGISTRATION NUMBER: NCT05022511.

AB - INTRODUCTION: The participation rate is higher in breast cancer screening than in cervical cancer (CCU) and colorectal cancer (CRC) screening. In this cluster-randomised study, we aim to evaluate an intervention offering home-based CCU and CRC screening to women when attending breast cancer screening if they are overdue for CCU and/or CRC screening.METHODS AND ANALYSIS: On intervention days, one of the five breast cancer screening units in the Central Denmark Region will be randomly allocated to intervention, whereas the remaining units will serve as control. Women attending breast cancer screening in the intervention unit will be offered information regarding their CCU and CRC screening history, and, if overdue, they will be offered self-sampling screening kits. For CCU screening, women aged 50-64 years will be offered a vaginal self-sampling kit for human papillomavirus testing. For CRC screening, women aged 50-69 years will be offered a kit to obtain a faecal immunochemical test. Women attending the control units will receive only standard care.After the intervention, a survey will be sent to all women in the intervention and control group, asking about their experience while attending breast cancer screening.Primary outcomes will be difference in the coverage in CCU and CRC screening 6 months after intervention between the intervention and the control group, and difference in participation rates 6 months after intervention for those who were overdue for CCU and/or CRC screening at the time of the intervention.ETHICS AND DISSEMINATION: The project is listed in the record of processing activities for research projects in the Central Denmark Region (R. No.: 1-16-02-217-21). According to the Danish Consolidation Act on Research Ethics Review of Health Research Project, this study was not notifiable to the Committee (R. No.: 1-10-72-1-21). The findings will be disseminated in peer-reviewed scientific journals.TRIAL REGISTRATION NUMBER: NCT05022511.

KW - Breast Neoplasms/diagnosis

KW - Cervix Uteri

KW - Colorectal Neoplasms/diagnosis

KW - Early Detection of Cancer/methods

KW - Female

KW - Humans

KW - Mass Screening/methods

KW - Randomized Controlled Trials as Topic

KW - Vaginal Smears

UR - http://www.scopus.com/inward/record.url?scp=85138392099&partnerID=8YFLogxK

U2 - 10.1136/bmjopen-2022-062824

DO - 10.1136/bmjopen-2022-062824

M3 - Journal article

C2 - 36137619

SN - 2044-6055

VL - 12

JO - BMJ Open

JF - BMJ Open

IS - 9

M1 - e062824

ER -