@article{f0cfcbad5c204d58931d73f5317d956d,
title = "The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity",
abstract = "Immunology; Microbiology Parasite; Cell Biology",
keywords = "Cell Biology, Immunology, Microbiology Parasite",
author = "Laurence Lecordier and Sophie Uzureau and Gilles Vanwalleghem and Magali Deleu and Crowet, {Jean Marc} and Paul Barry and Barry Moran and Paul Voorheis and Dumitru, {Andra Cristina} and Yoshiki Yamaryo-Bott{\'e} and Marc Dieu and Patricia Tebabi and Benoit Vanhollebeke and Laurence Lins and Bott{\'e}, {Cyrille Y.} and David Alsteens and Yves Dufr{\^e}ne and David P{\'e}rez-Morga and Nolan, {Derek P.} and Etienne Pays",
note = "Funding Information: We thank V. Flamant for the gift of μMT KO mice, S. Dean for the gift of pPOTv7 plasmid, A. Gauquier for help in the BL approach, and D. Monteyne for SEM analysis. This work was supported by the European Research Council (ERC 669007 -APOLs), the “Action de Recherches Concert{\'e}es” of the University of Brussels (ULB) (ARC ADV), and the Fonds de la Recherche Scientifique (F.R.S.-FNRS) ( PDR T.0159.13 to D.P.-M and PDR T.1003.14 to L.Lins and M.Deleu). The Center for Microscopy and Molecular Imaging is supported by the European Regional Development Fund and Wallonia. C.Y.B. and Y.Y. are supported by the Atip-Avenir and Fondation FINOVI programs (CNRS-INSERM-Finovi Atip-Avenir Apicolipid projects), and the Laboratoire d{\textquoteright}Excellence Parafrap , France (grant number ANR-11-LABX-0024 ). Computational resources have been provided by the Consortium des Equipements de Calcul Intensif (CECI), funded by the FNRS (Grant No. 2.5020.11 ). D.P.N. thanks the Wellcome Trust and Science Foundation Ireland (SFI) for financial support. M.D. and L.L. thank the FRS-FNRS for their positions as Senior Research Associates. Funding Information: We thank V. Flamant for the gift of ?MT KO mice, S. Dean for the gift of pPOTv7 plasmid, A. Gauquier for help in the BL approach, and D. Monteyne for SEM analysis. This work was supported by the European Research Council (ERC 669007-APOLs), the ?Action de Recherches Concert?es? of the University of Brussels (ULB) (ARC ADV), and the Fonds de la Recherche Scientifique (F.R.S.-FNRS) (PDR T.0159.13 to D.P.-M and PDR T.1003.14 to L.Lins and M.Deleu). The Center for Microscopy and Molecular Imaging is supported by the European Regional Development Fund and Wallonia. C.Y.B. and Y.Y. are supported by the Atip-Avenir and Fondation FINOVI programs (CNRS-INSERM-Finovi Atip-Avenir Apicolipid projects), and the Laboratoire d'Excellence Parafrap, France (grant number ANR-11-LABX-0024). Computational resources have been provided by the Consortium des Equipements de Calcul Intensif (CECI), funded by the FNRS (Grant No. 2.5020.11). D.P.N. thanks the Wellcome Trust and Science Foundation Ireland (SFI) for financial support. M.D. and L.L. thank the FRS-FNRS for their positions as Senior Research Associates. E.P. D.P.N. and L. Lecordier designed the research; L. Lecordier, S.U. G.V. M.Deleu, J.-M.C. P.B. B.M. A-C.D. Y.Y. M.Dieu, P.T. D.P.-M. and D.P.N. performed the research; B.V. L. Lins, C.Y.B. D.A. Y.D. D.P.-M. and D.P.N. supervised some aspects of the work; E.P. and D.P.N. wrote the paper. The authors declare that they have no competing financial interest. Publisher Copyright: {\textcopyright} 2020 The Author(s)",
year = "2020",
month = sep,
day = "25",
doi = "10.1016/j.isci.2020.101476",
language = "English",
volume = "23",
journal = "iScience",
issn = "2589-0042",
publisher = "Cell Press",
number = "9",
}