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The nose can be the focus of treatment and prophylactic approaches against COVID-19

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Review › Forskning › peer review

Infection with SARS-CoV-2 frequently commences in the nasal cavity, yet knowledge about this initial virus-host interaction is sparse. In this review, we update our current understanding of SARS-CoV-2 infection via the nasal epithelium and the associated local immune response. Furthermore, we present considerations to how this interaction may influence the clinical course of COVID-19 and the systemic immune response, and lastly touch upon the potential for intranasal vaccination, intranasal antiviral therapies and immunomodulatory approaches.

OriginalsprogEngelsk
TidsskriftUgeskrift for Laeger
Vol/bind183
Nummer37
ISSN0041-5782
StatusUdgivet - 13 sep. 2021

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