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The improvement of parturition duration by high intake of dietary fibre in late gestation is associated with gut microbiota and metabolome in sows

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

DOI

  • Yang Liu, Sichuan Agricultural University
    • ,
  • Pingping Jiang, Sun Yat-Sen University
    • ,
  • Nan Chen, Sichuan Agricultural University
    • ,
  • Yannan Jiang, Sun Yat-Sen University
    • ,
  • Ruinan Zhang, Sichuan Agricultural University
    • ,
  • Zhengfeng Fang, Sichuan Agricultural University
    • ,
  • Yan Lin, Sichuan Agricultural University
    • ,
  • Shengyu Xu, Sichuan Agricultural University
    • ,
  • Bin Feng, Sichuan Agricultural University
    • ,
  • Yong Zhuo, Sichuan Agricultural University
    • ,
  • De Wu, Sichuan Agricultural University
    • ,
  • Peter Kappel Theil
    • ,
  • Lianqiang Che, Sichuan Agricultural University

Prolonged parturition duration has been widely demonstrated to be a risk factor for incidence of stillbirth. This study evaluated the supply of dietary fibre on the parturition duration, gut microbiota and metabolome using sows as a model. A total of 40 Yorkshire sows were randomly given diet containing normal level of dietary fibre (NDF, 17·5 % dietary fibre) or high level of dietary fibre (HDF, 33·5 % dietary fibre). Faecal microbiota profiled with 16S rRNA amplicon sequencing, SCFA and metabolome in the faeces and plasma around parturition were compared between the dietary groups. Correlation analysis was conducted to further explore the potential associations between specific bacterial taxa and metabolites. Results showed that HDF diet significantly improved the parturition process as presented by the shorter parturition duration. HDF diet increased the abundance of the phyla Bacteroidetes and Synergistetes and multiple genera. Except for butyrate, SCFA levels in the faeces and plasma of sows at parturition were elevated in HDF group. The abundances of fifteen and twelve metabolites in the faeces and plasma, respectively, markedly differ between HDF and NDF sows. These metabolites are involved in energy metabolism and bacterial metabolism. Correlation analysis also showed associations between specific bacteria taxa and metabolites. Collectively, our study indicates that the improvement of parturition duration by high fibre intake in late gestation is associated with gut microbiota, production of SCFA and other metabolites, potentially serving for energy metabolism.

OriginalsprogEngelsk
TidsskriftBritish Journal of Nutrition
Vol/bind128
Nummer12
Sider (fra-til)2341-2352
ISSN0007-1145
DOI
StatusUdgivet - dec. 2022

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