The Epidemiology of Pheochromocytoma: Is the Incidence Increasing?

Publikation: KonferencebidragKonferenceabstrakt til konferenceForskning

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The Epidemiology of Pheochromocytoma : Is the Incidence Increasing? / Ebbehoj, A; Søndergaard, Esben; Trolle, Christian; Krag, Kirstine Stochholm; Poulsen, Per Løgstrup.

2017. 104-105 Abstract fra Kongres for Medicinsk Studenterforskning 2017, Nyborg, Danmark.

Publikation: KonferencebidragKonferenceabstrakt til konferenceForskning

Harvard

APA

CBE

Ebbehoj A, Søndergaard E, Trolle C, Krag KS, Poulsen PL. 2017. The Epidemiology of Pheochromocytoma: Is the Incidence Increasing?. Abstract fra Kongres for Medicinsk Studenterforskning 2017, Nyborg, Danmark.

MLA

Ebbehoj, A o.a.. The Epidemiology of Pheochromocytoma: Is the Incidence Increasing?. Kongres for Medicinsk Studenterforskning 2017, 16 mar. 2017, Nyborg, Danmark, Konferenceabstrakt til konference, 2017.

Vancouver

Ebbehoj A, Søndergaard E, Trolle C, Krag KS, Poulsen PL. The Epidemiology of Pheochromocytoma: Is the Incidence Increasing?. 2017. Abstract fra Kongres for Medicinsk Studenterforskning 2017, Nyborg, Danmark.

Author

Ebbehoj, A ; Søndergaard, Esben ; Trolle, Christian ; Krag, Kirstine Stochholm ; Poulsen, Per Løgstrup. / The Epidemiology of Pheochromocytoma : Is the Incidence Increasing?. Abstract fra Kongres for Medicinsk Studenterforskning 2017, Nyborg, Danmark.

Bibtex

@conference{fab42509af864f09a0e1081f36434727,
title = "The Epidemiology of Pheochromocytoma: Is the Incidence Increasing?",
abstract = "Background: Although pheochromocytoma is an exceedingly rare adrenal tumour, it is a frequent diagnostic dilemma due to its potential life-threatening nature. There is a widespread perception of an increase in incidence over the recent years, but no data on time trends exist.Methods: Data were obtained from The Danish National Registry of Patients, The Danish Registry of Causes of Death, and The National Pathology Registry for all persons registered with pheochromocytoma or catecholamine hypersecretion between 1/1/1977 and 31/12/2015. Health records were reviewed to validate the diagnosis for all patients in the Northern and Central Regions of Denmark. Incidence rates were calculated using Poisson regression and time trends were analysed with year as a continuous explanatory variable.Results: We found an increasing trend from 2.06 (CI95% 1.68-2.49) per million person-years 1977-2006 to 4.65 (CI95% 3.72-5.82) 2007-2015. In addition, patients were older at diagnosis (p<0.001) and less symptomatic (p=0.032). No changes were observed in symptom duration, tumour size or level of catecholamines.Conclusion: The incidence of pheochromocytoma has increased significantly in recent years, presumably due to the increased use of imaging studies leading to incidentally found adrenal tumours. These older incidentaloma patients appear to represent a new group of pheochromocytoma not previously diagnosed.",
keywords = "Pheochromocytoma, Incidence, Epidemiology",
author = "A Ebbehoj and Esben S{\o}ndergaard and Christian Trolle and Krag, {Kirstine Stochholm} and Poulsen, {Per L{\o}gstrup}",
year = "2017",
month = mar,
day = "17",
language = "English",
pages = "104--105",
note = "null ; Conference date: 16-03-2017 Through 19-03-2017",
url = "http://studenterforskning.dk/studenterkongres/",

}

RIS

TY - ABST

T1 - The Epidemiology of Pheochromocytoma

AU - Ebbehoj, A

AU - Søndergaard, Esben

AU - Trolle, Christian

AU - Krag, Kirstine Stochholm

AU - Poulsen, Per Løgstrup

PY - 2017/3/17

Y1 - 2017/3/17

N2 - Background: Although pheochromocytoma is an exceedingly rare adrenal tumour, it is a frequent diagnostic dilemma due to its potential life-threatening nature. There is a widespread perception of an increase in incidence over the recent years, but no data on time trends exist.Methods: Data were obtained from The Danish National Registry of Patients, The Danish Registry of Causes of Death, and The National Pathology Registry for all persons registered with pheochromocytoma or catecholamine hypersecretion between 1/1/1977 and 31/12/2015. Health records were reviewed to validate the diagnosis for all patients in the Northern and Central Regions of Denmark. Incidence rates were calculated using Poisson regression and time trends were analysed with year as a continuous explanatory variable.Results: We found an increasing trend from 2.06 (CI95% 1.68-2.49) per million person-years 1977-2006 to 4.65 (CI95% 3.72-5.82) 2007-2015. In addition, patients were older at diagnosis (p<0.001) and less symptomatic (p=0.032). No changes were observed in symptom duration, tumour size or level of catecholamines.Conclusion: The incidence of pheochromocytoma has increased significantly in recent years, presumably due to the increased use of imaging studies leading to incidentally found adrenal tumours. These older incidentaloma patients appear to represent a new group of pheochromocytoma not previously diagnosed.

AB - Background: Although pheochromocytoma is an exceedingly rare adrenal tumour, it is a frequent diagnostic dilemma due to its potential life-threatening nature. There is a widespread perception of an increase in incidence over the recent years, but no data on time trends exist.Methods: Data were obtained from The Danish National Registry of Patients, The Danish Registry of Causes of Death, and The National Pathology Registry for all persons registered with pheochromocytoma or catecholamine hypersecretion between 1/1/1977 and 31/12/2015. Health records were reviewed to validate the diagnosis for all patients in the Northern and Central Regions of Denmark. Incidence rates were calculated using Poisson regression and time trends were analysed with year as a continuous explanatory variable.Results: We found an increasing trend from 2.06 (CI95% 1.68-2.49) per million person-years 1977-2006 to 4.65 (CI95% 3.72-5.82) 2007-2015. In addition, patients were older at diagnosis (p<0.001) and less symptomatic (p=0.032). No changes were observed in symptom duration, tumour size or level of catecholamines.Conclusion: The incidence of pheochromocytoma has increased significantly in recent years, presumably due to the increased use of imaging studies leading to incidentally found adrenal tumours. These older incidentaloma patients appear to represent a new group of pheochromocytoma not previously diagnosed.

KW - Pheochromocytoma

KW - Incidence

KW - Epidemiology

M3 - Conference abstract for conference

SP - 104

EP - 105

Y2 - 16 March 2017 through 19 March 2017

ER -