The Delphi and GRADE methodology used in the PSOGI 2018 consensus statement on Pseudomyxoma Peritonei and Peritoneal Mesothelioma

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisReviewForskningpeer review

DOI

  • R J Lurvink, Catharina Hospital
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  • L Villeneuve, Hospices Civils de Lyon
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  • K Govaerts, Department of Surgical Oncology, Hospital Oost-Limburg, Genk, Belgium.
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  • I H J T de Hingh, Department of Surgical Oncology, Catharina Cancer Institute, Eindhoven, the Netherlands; Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands.
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  • B J Moran, Peritoneal Malignancy Institute, North-Hampshire Hospital, Basingstoke, United Kingdom.
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  • M Deraco, Department of Surgery, Peritoneal Surface Malignancy Unit, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.
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  • K Van der Speeten, Department of Surgical Oncology, Hospital Oost-Limburg, Genk, Belgium.
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  • O Glehen, Department of Digestive Surgery, Centre Hospitalier Lyon Sud, Lyon, France.
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  • V Kepenekian, Department of Digestive Surgery, Centre Hospitalier Lyon Sud, Lyon, France; EMR 3738, Lyon 1 University, Lyon, France.
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  • S Kusamura, Department of Surgery, Peritoneal Surface Malignancy Unit, Fondazione IRCCS Istituto Nazionale Dei Tumori di Milano, Milan, Italy.
  • ,
  • List of PSOGI collaborators

Pseudomyxoma Peritonei (PMP) and Peritoneal Mesothelioma (PM) are both rare peritoneal malignancies. Currently, affected patients may be treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy offering long-term survival or even cure in selected patients. However, many issues regarding the optimal treatment strategy are currently under debate. To aid physicians involved in the treatment of these patients in clinical decision making, the PSOGI executive committee proposed to create a consensus statement on PMP and PM. This manuscript describes the methodology of the consensus process. The Delphi technique is a reliable method for attaining consensus on a topic that lacks scientific evidence through multiple voting rounds which feeds back responses to the participants in between rounds. The GRADE system provides a structured framework for presenting and grading the available evidence. Separate questionnaires were created for PMP and PM and sent during two voting rounds to 80 and 38 experts, respectively. A consensus threshold of 51.0% was chosen. After the second round, consensus was reached on 92.9%-100.0% of the questions. The results were presented and discussed in the plenary session at the PSOGI 2018 international meeting in Paris. A third round for the remaining issues is currently in progress. In conclusion, using the Delphi technique and GRADE methodology, consensus was reached in many issues regarding the treatment of PM and PMP amongst an international panel of experts. The main results will be published in the near future.

OriginalsprogEngelsk
TidsskriftEuropean Journal of Surgical Oncology
Vol/bind47
Nummer1
Sider (fra-til)4-10
Antal sider7
ISSN0748-7983
DOI
StatusUdgivet - jan. 2021

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