Institut for Odontologi og Oral Sundhed

TY - JOUR

T1 - Temporal summation of painful heat stimulation is facilitated in trigeminal and extratrigeminal regions in painful myofascial temporomandibular disorders

T2 - Evidence from a case-control study

AU - Zhou, Pin

AU - Li, Yuan

AU - Zhang, Jinglu

AU - Chen, Yaming

AU - Wang, Kelun

AU - Svensson, Peter

PY - 2019

Y1 - 2019

N2 - Aims: To determine whether patients with painful myofascial temporomandibular disorders (TMD) demonstrate facilitated temporal summation (TS) responses to painful heat stimuli applied to the painful trigeminal and extratrigeminal regions and whether there is a side difference in the trigeminal region for myofascial TMD pain patients compared to healthy controls. Methods: Twenty female Chinese myofascial TMD pain patients and 20 age-matched female volunteers participated in this case-control study. Thermal detection thresholds, thermal pain thresholds, and TS of 20 repetitive noxious thermal stimuli were measured on the skin above the masseter muscle on both sides and the thenar eminence of the less painful side/dominant hand. Numeric rating scale (NRS) scores of pain were provided after the 1st, 5th, 10th, 15th, and 20th stimuli, and TS was calculated as the highest NRS score minus the first NRS score in each test. Results: Evidence of TS was found in the trigeminal and extratrigeminal regions for both groups, but with facilitated TS responses in myofascial TMD pain patients (P < .001). Within the myofascial TMD group and control group, there were no side-to-side differences (P > .289). Interestingly, the repetition of the TS test was associated with facilitated responses in myofascial TMD pain patients (P < .001). Conclusion: The current findings suggest TS of painful heat stimulation is facilitated in myofascial TMD pain patients with no side difference in the trigeminal region.

AB - Aims: To determine whether patients with painful myofascial temporomandibular disorders (TMD) demonstrate facilitated temporal summation (TS) responses to painful heat stimuli applied to the painful trigeminal and extratrigeminal regions and whether there is a side difference in the trigeminal region for myofascial TMD pain patients compared to healthy controls. Methods: Twenty female Chinese myofascial TMD pain patients and 20 age-matched female volunteers participated in this case-control study. Thermal detection thresholds, thermal pain thresholds, and TS of 20 repetitive noxious thermal stimuli were measured on the skin above the masseter muscle on both sides and the thenar eminence of the less painful side/dominant hand. Numeric rating scale (NRS) scores of pain were provided after the 1st, 5th, 10th, 15th, and 20th stimuli, and TS was calculated as the highest NRS score minus the first NRS score in each test. Results: Evidence of TS was found in the trigeminal and extratrigeminal regions for both groups, but with facilitated TS responses in myofascial TMD pain patients (P < .001). Within the myofascial TMD group and control group, there were no side-to-side differences (P > .289). Interestingly, the repetition of the TS test was associated with facilitated responses in myofascial TMD pain patients (P < .001). Conclusion: The current findings suggest TS of painful heat stimulation is facilitated in myofascial TMD pain patients with no side difference in the trigeminal region.

KW - Hyperalgesia

KW - Myofascial pain

KW - Temporal summation

KW - Temporomandibular disorders

KW - Thermal detection

UR - http://www.scopus.com/inward/record.url?scp=85065218345&partnerID=8YFLogxK

U2 - 10.11607/ofph.2248

DO - 10.11607/ofph.2248

M3 - Journal article

C2 - 30726863

AN - SCOPUS:85065218345

VL - 33

SP - 174

EP - 182

JO - Journal of orofacial pain

JF - Journal of orofacial pain

SN - 1064-6655

IS - 2

ER -