Aarhus University Seal / Aarhus Universitets segl

Targeting the nuclear RNA exosome: Poly(A) binding proteins enter the stage

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Dokumenter

DOI

Centrally positioned in nuclear RNA metabolism, the exosome deals with virtually all transcript types. This 3'-5' exo- and endo-nucleolytic degradation machine is guided to its RNA targets by adaptor proteins that enable substrate recognition. Recently, the discovery of the 'Poly(A) tail exosome targeting (PAXT)' connection as an exosome adaptor to human nuclear polyadenylated transcripts has relighted the interest of poly(A) binding proteins (PABPs) in both RNA productive and destructive processes.

OriginalsprogEngelsk
TidsskriftRNA Biology
Vol/bind14
Nummer7
Sider (fra-til)820-826
Antal sider7
ISSN1547-6286
DOI
StatusUdgivet - 2017

Se relationer på Aarhus Universitet Citationsformater

Download-statistik

Ingen data tilgængelig

ID: 112850660