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Structural parcellation of the thalamus using shortest-path tractography

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  • Niklas Kasenburg, Danmark
  • Sune Darkner
  • ,
  • Ute Hahn
  • Matthew Liptrot, Danmark
  • Aasa Feragen, Danmark
We demonstrate how structural parcellation can be implemented using shortest-path tractography, thereby addressing some of the shortcomings of the conventional approaches. In particular, our algorithm quantifies, via p-values, the confidence that a voxel in the parcellated region is connected to
each cortical target region. Calculation of these statistical measures is derived from a rank-based test on the histogram of tract-based scores from all the shortest-paths found between the seed voxel and each voxel within the target region.
Using data from the Human Connectome Project, we show that parcellation of the thalamus results in p-value maps that are spatially coherent across subjects. Whilst some agreement to a hard segmentation as in previous studies is observed, the soft segmentation exhibits better stability for voxels connected to multiple target regions.
TidsskriftIEEE Xplore
Sider (fra-til)559-563
Antal sider5
StatusUdgivet - 2016
BegivenhedIEEE 13th International Symposium on Biomedical Imaging -
Varighed: 13 apr. 201616 apr. 2016
Konferencens nummer: 13


KonferenceIEEE 13th International Symposium on Biomedical Imaging

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