Soluble Receptor for Advanced Glycation End Product: A Biomarker for Acute Coronary Syndrome

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DOI

The receptor of advanced glycation end products (RAGE) and its ligands are linked to the pathogenesis of coronary artery disease (CAD), and circulating soluble receptor of advanced glycation end products (sRAGE), reflecting the RAGE activity, is suggested as a potential biomarker. Elevated sRAGE levels are reported in relation to acute ischemia and this review focuses on the role of sRAGE as a biomarker for the acute coronary syndrome (ACS). The current studies demonstrated that sRAGE levels are elevated in relation to ACS, however during a very narrow time period, indicating that the time of sampling needs attention. Interestingly, activation of RAGE may influence the pathogenesis and reflection in sRAGE levels in acute and stable CAD differently.

OriginalsprogEngelsk
Artikelnummer815942
TidsskriftBioMed Research International
Vol/bind2015
Antal sider7
ISSN2314-6133
DOI
StatusUdgivet - 2015

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