SNP markers associated with body size and pelt length in American mink (Neovison vison)

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SNP markers associated with body size and pelt length in American mink (Neovison vison). / Cai, Zexi; Villumsen, Trine Michelle; Asp, Torben; Guldbrandtsen, Bernt; Sahana, Goutam; Lund, Mogens Sandø.

I: BMC Genetics, Bind 19, Nr. 1, 103, 12.11.2018.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

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@article{bfecf43767d94f8faac20f07ef381f85,
title = "SNP markers associated with body size and pelt length in American mink (Neovison vison)",
abstract = "BACKGROUND: Identification of genes underlying production traits is a key aim of the mink research community. Recent availability of genomic tools have opened the possibility for faster genetic progress in mink breeding. Availability of mink genome assembly allows genome-wide association studies in mink. RESULTS: In this study, we used genotyping-by-sequencing to obtain single nucleotide polymorphism (SNP) genotypes of 2496 mink. After multiple rounds of filtering, we retained 28,336 high quality SNPs and 2352 individuals for a genome-wide association study (GWAS). We performed the first GWAS for body weight, behavior, along with 10 traits related to fur quality in mink. CONCLUSIONS: Combining association results with existing functional information of genes and mammalian phenotype databases, we proposed WWC3, MAP2K4, SLC7A1 and USP22 as candidate genes for body weight and pelt length in mink.",
keywords = "American mink, Body weight, GWAS, Pelt length, Production trait",
author = "Zexi Cai and Villumsen, {Trine Michelle} and Torben Asp and Bernt Guldbrandtsen and Goutam Sahana and Lund, {Mogens Sand{\o}}",
year = "2018",
month = nov,
day = "12",
doi = "10.1186/s12863-018-0688-6",
language = "English",
volume = "19",
journal = "B M C Genetics",
issn = "1471-2156",
publisher = "BioMed Central Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - SNP markers associated with body size and pelt length in American mink (Neovison vison)

AU - Cai, Zexi

AU - Villumsen, Trine Michelle

AU - Asp, Torben

AU - Guldbrandtsen, Bernt

AU - Sahana, Goutam

AU - Lund, Mogens Sandø

PY - 2018/11/12

Y1 - 2018/11/12

N2 - BACKGROUND: Identification of genes underlying production traits is a key aim of the mink research community. Recent availability of genomic tools have opened the possibility for faster genetic progress in mink breeding. Availability of mink genome assembly allows genome-wide association studies in mink. RESULTS: In this study, we used genotyping-by-sequencing to obtain single nucleotide polymorphism (SNP) genotypes of 2496 mink. After multiple rounds of filtering, we retained 28,336 high quality SNPs and 2352 individuals for a genome-wide association study (GWAS). We performed the first GWAS for body weight, behavior, along with 10 traits related to fur quality in mink. CONCLUSIONS: Combining association results with existing functional information of genes and mammalian phenotype databases, we proposed WWC3, MAP2K4, SLC7A1 and USP22 as candidate genes for body weight and pelt length in mink.

AB - BACKGROUND: Identification of genes underlying production traits is a key aim of the mink research community. Recent availability of genomic tools have opened the possibility for faster genetic progress in mink breeding. Availability of mink genome assembly allows genome-wide association studies in mink. RESULTS: In this study, we used genotyping-by-sequencing to obtain single nucleotide polymorphism (SNP) genotypes of 2496 mink. After multiple rounds of filtering, we retained 28,336 high quality SNPs and 2352 individuals for a genome-wide association study (GWAS). We performed the first GWAS for body weight, behavior, along with 10 traits related to fur quality in mink. CONCLUSIONS: Combining association results with existing functional information of genes and mammalian phenotype databases, we proposed WWC3, MAP2K4, SLC7A1 and USP22 as candidate genes for body weight and pelt length in mink.

KW - American mink

KW - Body weight

KW - GWAS

KW - Pelt length

KW - Production trait

UR - http://www.scopus.com/inward/record.url?scp=85056328142&partnerID=8YFLogxK

U2 - 10.1186/s12863-018-0688-6

DO - 10.1186/s12863-018-0688-6

M3 - Journal article

C2 - 30419805

AN - SCOPUS:85056328142

VL - 19

JO - B M C Genetics

JF - B M C Genetics

SN - 1471-2156

IS - 1

M1 - 103

ER -