Aarhus University Seal / Aarhus Universitets segl

Similar early mortality risk after cemented compared with cementless total hip arthroplasty for primary osteoarthritis: data from 188,606 surgeries in the Nordic Arthroplasty Register Association database

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  • Alma B. Pedersen
  • Aurélie Mailhac
  • Anne Garland, Uppsala University, Registercentrum Västra Götaland
  • ,
  • Søren Overgaard, Syddansk Universitet
  • ,
  • Ove Furnes, University of Bergen
  • ,
  • Stein Atle Lie, University of Bergen
  • ,
  • Anne Marie Fenstad, University of Bergen
  • ,
  • Cecilia Rogmark, Lund University, Registercentrum Västra Götaland
  • ,
  • Johan Kärrholm, Registercentrum Västra Götaland, University of Gothenburg
  • ,
  • Ola Rolfson, Registercentrum Västra Götaland, University of Gothenburg
  • ,
  • Jaason Haapakoski, National Institute for Health and Welfare
  • ,
  • Antti Eskelinen, National Institute for Health and Welfare, Tampere University
  • ,
  • Keijo T. Mäkelä, National Institute for Health and Welfare, University of Turku
  • ,
  • Nils P. Hailer, Uppsala University, Registercentrum Västra Götaland

Background and purpose — Current literature indicates no difference in 90-day mortality after cemented compared with cementless total hip arthroplasty (THA). However, previous studies are hampered by potential selection bias and suboptimal adjustment for comorbidity confounding. Therefore, we examined the comorbidity-adjusted mortality up to 90 days after cemented compared with cementless THA performed due to osteoarthritis. Patients and methods — Using the Nordic Arthroplasty Register Association database, 2005–2013, we included 108,572 cemented and 80,034 cementless THA due to osteoarthritis. We calculated the Charlson comorbidity index of each patient based on data from national patient registers. The Kaplan–Meier method was used to estimate unadjusted all-cause mortality. Cox regression was used to estimate hazard ratios (HR) with 95% confidence intervals (CI) for 14, 30-, and 90-day mortality comparing cemented with cementless THA, adjusting for age, sex, comorbidity, nation, and year of surgery. Results — Cumulative all-cause mortality within 90 days was 0.41% (CI 0.37–0.46) after cemented and 0.26% (CI 0.22–0.30) after cementless THA. The adjusted HR for cemented vs. cementless fixation was 0.97 (CI 0.79–1.2), and similar risk estimates were obtained for mortality within 14 (adjusted HR 0.91 [CI 0.64–1.3]) and 30 days (adjusted HR 0.94 [CI 0.71–1.3]). We found no clinically relevant differences in mortality between cemented and cementless THA in analyses stratified by age, sex, Charlson comorbidity index, or year of surgery. Interpretation — After adjustment for comorbidity as an important confounder, we observed similar early mortality between the 2 fixation techniques.

OriginalsprogEngelsk
TidsskriftActa Orthopaedica
Vol/bind92
Nummer1
Sider (fra-til)47-53
Antal sider7
ISSN1745-3674
DOI
StatusUdgivet - 2021

Bibliografisk note

Publisher Copyright:
© 2020 The Author(s). Published by Taylor & Francis on behalf of the Nordic Orthopedic Federation.

Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.

Se relationer på Aarhus Universitet Citationsformater

ID: 207555381