Serum mannan-binding lectin-associated serine protease 2 levels in colorectal cancer: relation to recurrence and mortality

Henriette Ytting, Ib Jarle Christensen, Steffen Thiel, Jens Christian Jensenius, Hans Jørgen Nielsen

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Abstract

Mannan-binding lectin-associated serine protease 2 (MASP-2) is a plasma protein involved in inflammatory processes. MASP-2 circulates in complex with the protein mannan-binding lectin (MBL) or ficolins, and is activated to recruit the complement system when MBL binds to its targets. The level of MASP-2 is genetically determined, and the aim of the present study was to evaluate the effect of MASP-2 levels on postoperative infection, recurrence and survival.
OriginalsprogEngelsk
TidsskriftClinical Cancer Research
Vol/bind11
Nummer4
Sider (fra-til)1441-6
Antal sider6
ISSN1078-0432
DOI
StatusUdgivet - 2005

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