Semen quality among young healthy men taking protein supplements

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  • Sandra Søgaard Tøttenborg, Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, Univsersity of Copenhagen, Copenhagen, Denmark. Electronic address: sandra.soegaard.toettenborg@regionh.dk., Danmark
  • Clara Helene Glazer, Københavns Universitet, Danmark
  • Katia Keglberg Hærvig, Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, Univsersity of Copenhagen, Copenhagen, Denmark; Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Danmark
  • Birgit Bjerre Høyer, Department of Occupational and Environmental Medicine, Copenhagen University Hospital Bispebjerg-Frederiksberg, DK-2400 Copenhagen NW, Denmark.
  • ,
  • Gunnar Toft
  • Karin Sørig Hougaard, Københavns Universitet, Danmark
  • Esben Meulengracht Flachs, Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, Univsersity of Copenhagen, Copenhagen, Denmark., Danmark
  • Laura Deen, Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, Univsersity of Copenhagen, Copenhagen, Denmark; Department of Public Health, University of Copenhagen, Copenhagen, Denmark., Danmark
  • Jens Peter Ellekilde Bonde, Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospital, Univsersity of Copenhagen, Copenhagen, Denmark; Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
  • ,
  • Cecilia Høst Ramlau-Hansen

OBJECTIVE: To study the association between use of protein supplements (PS) and semen quality among young men.

DESIGN: Cross-sectional study.

SETTING: Not applicable PATIENT(S): We used data from the Fetal Programming of Semen Quality (FEPOS) cohort, which is a subsample of 778 men whose mothers enrolled in the Danish National Birth Cohort 1996-2002.

INTERVENTION(S): Semen samples were collected from April 2017 to March 2019. Relative difference in semen characteristics according to self-reported PS use was estimated with negative binomial regression adjusting for lifestyle factors including exercise, body mass index, and use of anabolic steroids, and maternal and paternal factors potentially confounding the association between PS and semen quality.

MAIN OUTCOME MEASURE(S): Negative binomial regression yielded the best fit and was used to estimate the percent difference with 95% confidence intervals in semen volume, sperm concentration, total sperm count, proportions of progressive, nonprogressive, and immotile sperm, and percentage of morphologically normal sperm in former and current users of PS relative to never users.

RESULT(S): PS was used currently by 28% and formerly by 24% of participants. PS use was not associated with reduced semen quality in terms of semen volume, sperm concentration, total sperm count, morphology, or motility in either crude or adjusted analyses.

CONCLUSION: This study showed no association between use of PS and semen quality characteristics. Still, we encourage others to repeat the study, as even a small harmful effect would have a large impact on the population level because of the widespread use of PS among young men.

OriginalsprogEngelsk
TidsskriftFertility and Sterility
Vol/bind114
Nummer1
Sider (fra-til)89-96
Antal sider7
ISSN0015-0282
DOI
StatusUdgivet - jul. 2020

Bibliografisk note

Copyright © 2020 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Se relationer på Aarhus Universitet Citationsformater

ID: 187079520