Reproducibility of semi-automatic coronary plaque quantification in coronary CT angiography with sub-mSv radiation dose

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Standard

Reproducibility of semi-automatic coronary plaque quantification in coronary CT angiography with sub-mSv radiation dose. / Øvrehus, Kristian Altern; Schuhbaeck, Annika; Marwan, Mohamed; Achenbach, Stephan; Nørgaard, Bjarne Linde; Bøtker, Hans Erik; Dey, Damini.

I: Journal of Cardiovascular Computed Tomography, 02.12.2015.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Øvrehus, KA, Schuhbaeck, A, Marwan, M, Achenbach, S, Nørgaard, BL, Bøtker, HE & Dey, D 2015, 'Reproducibility of semi-automatic coronary plaque quantification in coronary CT angiography with sub-mSv radiation dose', Journal of Cardiovascular Computed Tomography. https://doi.org/10.1016/j.jcct.2015.11.003

APA

Øvrehus, K. A., Schuhbaeck, A., Marwan, M., Achenbach, S., Nørgaard, B. L., Bøtker, H. E., & Dey, D. (2015). Reproducibility of semi-automatic coronary plaque quantification in coronary CT angiography with sub-mSv radiation dose. Journal of Cardiovascular Computed Tomography. https://doi.org/10.1016/j.jcct.2015.11.003

CBE

Øvrehus KA, Schuhbaeck A, Marwan M, Achenbach S, Nørgaard BL, Bøtker HE, Dey D. 2015. Reproducibility of semi-automatic coronary plaque quantification in coronary CT angiography with sub-mSv radiation dose. Journal of Cardiovascular Computed Tomography. https://doi.org/10.1016/j.jcct.2015.11.003

MLA

Vancouver

Øvrehus KA, Schuhbaeck A, Marwan M, Achenbach S, Nørgaard BL, Bøtker HE o.a. Reproducibility of semi-automatic coronary plaque quantification in coronary CT angiography with sub-mSv radiation dose. Journal of Cardiovascular Computed Tomography. 2015 dec 2. https://doi.org/10.1016/j.jcct.2015.11.003

Author

Øvrehus, Kristian Altern ; Schuhbaeck, Annika ; Marwan, Mohamed ; Achenbach, Stephan ; Nørgaard, Bjarne Linde ; Bøtker, Hans Erik ; Dey, Damini. / Reproducibility of semi-automatic coronary plaque quantification in coronary CT angiography with sub-mSv radiation dose. I: Journal of Cardiovascular Computed Tomography. 2015.

Bibtex

@article{b066112ba1ff4b69bbe71ceb17a8807a,
title = "Reproducibility of semi-automatic coronary plaque quantification in coronary CT angiography with sub-mSv radiation dose",
abstract = "INTRODUCTION: Coronary computed tomographic angiography (CTA) can characterize coronary atherosclerotic plaque components as calcified and non-calcified. Quantitative measurements of coronary plaque burden by coronary CTA may play a role in serial studies to determine disease progression or response to medical therapies. The reproducibility from repeated assessment of such quantitative measurements from low-radiation dose coronary CTA has not been previously assessed.PURPOSE: To evaluate the interscan, interobserver and intraobserver reproducibility for coronary plaque volume assessment using semi-automatic plaque analyses algorithm in low radiation dose coronary CTA.METHODS: In 50 consecutive patients undergoing two 128-slice dual source CT scans within 12 days with a mean radiation dose of 0.7 mSv per coronary CTA, the interscan, interobserver and intraobserver reproducibility of coronary plaque assessment using validated software (AutoPlaq) were evaluated.RESULTS: Interscan, interobserver and intraobserver agreement for non-calcified and calcified plaque volumes were excellent (Spearman rho 0.87-0.99). Interscan mean percentage difference in non-calcified and calcified plaque volumes were 0.1% (p = 0.8) and 1.9% (p = 0.19) with limits of agreement of ±11% and ±48.5%; per inter- and intraobserver mean percentage differences were 0.1% (p = 0.25) and 0.3% (p = 0.001), and 0.3% (p = 0.33) and 0.4% (p = 0.59) with limits of agreement of ±7% and ±32.9%, and ±6.6% and ±32.1%, respectively.CONCLUSION: A semi-automatic plaque assessment algorithm in repeated low radiation dose coronary CTA allows for high reproducibility of coronary plaque characterization and quantification measures.",
author = "{\O}vrehus, {Kristian Altern} and Annika Schuhbaeck and Mohamed Marwan and Stephan Achenbach and N{\o}rgaard, {Bjarne Linde} and B{\o}tker, {Hans Erik} and Damini Dey",
note = "Copyright {\textcopyright} 2015. Published by Elsevier Inc.",
year = "2015",
month = dec,
day = "2",
doi = "10.1016/j.jcct.2015.11.003",
language = "English",
journal = "Journal of Cardiovascular Computed Tomography",
issn = "1934-5925",
publisher = "Elsevier Inc.",

}

RIS

TY - JOUR

T1 - Reproducibility of semi-automatic coronary plaque quantification in coronary CT angiography with sub-mSv radiation dose

AU - Øvrehus, Kristian Altern

AU - Schuhbaeck, Annika

AU - Marwan, Mohamed

AU - Achenbach, Stephan

AU - Nørgaard, Bjarne Linde

AU - Bøtker, Hans Erik

AU - Dey, Damini

N1 - Copyright © 2015. Published by Elsevier Inc.

PY - 2015/12/2

Y1 - 2015/12/2

N2 - INTRODUCTION: Coronary computed tomographic angiography (CTA) can characterize coronary atherosclerotic plaque components as calcified and non-calcified. Quantitative measurements of coronary plaque burden by coronary CTA may play a role in serial studies to determine disease progression or response to medical therapies. The reproducibility from repeated assessment of such quantitative measurements from low-radiation dose coronary CTA has not been previously assessed.PURPOSE: To evaluate the interscan, interobserver and intraobserver reproducibility for coronary plaque volume assessment using semi-automatic plaque analyses algorithm in low radiation dose coronary CTA.METHODS: In 50 consecutive patients undergoing two 128-slice dual source CT scans within 12 days with a mean radiation dose of 0.7 mSv per coronary CTA, the interscan, interobserver and intraobserver reproducibility of coronary plaque assessment using validated software (AutoPlaq) were evaluated.RESULTS: Interscan, interobserver and intraobserver agreement for non-calcified and calcified plaque volumes were excellent (Spearman rho 0.87-0.99). Interscan mean percentage difference in non-calcified and calcified plaque volumes were 0.1% (p = 0.8) and 1.9% (p = 0.19) with limits of agreement of ±11% and ±48.5%; per inter- and intraobserver mean percentage differences were 0.1% (p = 0.25) and 0.3% (p = 0.001), and 0.3% (p = 0.33) and 0.4% (p = 0.59) with limits of agreement of ±7% and ±32.9%, and ±6.6% and ±32.1%, respectively.CONCLUSION: A semi-automatic plaque assessment algorithm in repeated low radiation dose coronary CTA allows for high reproducibility of coronary plaque characterization and quantification measures.

AB - INTRODUCTION: Coronary computed tomographic angiography (CTA) can characterize coronary atherosclerotic plaque components as calcified and non-calcified. Quantitative measurements of coronary plaque burden by coronary CTA may play a role in serial studies to determine disease progression or response to medical therapies. The reproducibility from repeated assessment of such quantitative measurements from low-radiation dose coronary CTA has not been previously assessed.PURPOSE: To evaluate the interscan, interobserver and intraobserver reproducibility for coronary plaque volume assessment using semi-automatic plaque analyses algorithm in low radiation dose coronary CTA.METHODS: In 50 consecutive patients undergoing two 128-slice dual source CT scans within 12 days with a mean radiation dose of 0.7 mSv per coronary CTA, the interscan, interobserver and intraobserver reproducibility of coronary plaque assessment using validated software (AutoPlaq) were evaluated.RESULTS: Interscan, interobserver and intraobserver agreement for non-calcified and calcified plaque volumes were excellent (Spearman rho 0.87-0.99). Interscan mean percentage difference in non-calcified and calcified plaque volumes were 0.1% (p = 0.8) and 1.9% (p = 0.19) with limits of agreement of ±11% and ±48.5%; per inter- and intraobserver mean percentage differences were 0.1% (p = 0.25) and 0.3% (p = 0.001), and 0.3% (p = 0.33) and 0.4% (p = 0.59) with limits of agreement of ±7% and ±32.9%, and ±6.6% and ±32.1%, respectively.CONCLUSION: A semi-automatic plaque assessment algorithm in repeated low radiation dose coronary CTA allows for high reproducibility of coronary plaque characterization and quantification measures.

U2 - 10.1016/j.jcct.2015.11.003

DO - 10.1016/j.jcct.2015.11.003

M3 - Journal article

C2 - 26712694

JO - Journal of Cardiovascular Computed Tomography

JF - Journal of Cardiovascular Computed Tomography

SN - 1934-5925

ER -