Recommendations for Preclinical Renal MRI: A Comprehensive Open-Access Protocol Collection to Improve Training, Reproducibility, and Comparability of Studies

Publikation: Bidrag til bog/antologi/rapport/proceedingBidrag til bog/antologiFormidling

DOI

  • Andreas Pohlmann, Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Siemens Healthcare Diagnostics Holding GmbH, Eschborn,
  • Susan J Back, The Children's Hospital of Philadelphia, Philadelphia, PA
  • ,
  • Andrea Fekete, Semmelweis Univ, Semmelweis University, Dept Vasc Surg
  • ,
  • Iris Friedli, Antaros Medical
  • ,
  • Stefanie Hectors, Translational and Molecular Imaging Institute and Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • ,
  • Neil Peter Jerome, Norwegian University for Science and Technology (NTNU)
  • ,
  • Min-Chi Ku, Max Delbrück Center for Molecular Medicine in the Helmholtz Association
  • ,
  • Dario Livio Longo, Institute of Biostructures and Bioimaging (IBB)
  • ,
  • Martin Meier, ZTL-Imaging Center, Hannover Medical School, Hannover
  • ,
  • Jason M Millward, Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association
  • ,
  • João S Periquito, Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association
  • ,
  • Erdmann Seeliger, Institute of Physiology, Charité-University Medicine Berlin, Berlin, Germany.
  • ,
  • Suraj D Serai, The Children's Hospital of Philadelphia, Philadelphia, PA
  • ,
  • Sonia Waiczies, Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association
  • ,
  • Steven Sourbron, The University of Sheffield
  • ,
  • Christoffer Laustsen
  • Thoralf Niendorf, Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association

Renal MRI holds incredible promise for making a quantum leap in improving diagnosis and care of patients with a multitude of diseases, by moving beyond the limitations and restrictions of current routine clinical practice. Clinical and preclinical renal MRI is advancing with ever increasing rapidity, and yet, aside from a few examples of renal MRI in routine use, it is still not good enough. Several roadblocks are still delaying the pace of progress, particularly inefficient education of renal MR researchers, and lack of harmonization of approaches that limits the sharing of results among multiple research groups.Here we aim to address these limitations for preclinical renal MRI (predominantly in small animals), by providing a comprehensive collection of more than 40 publications that will serve as a foundational resource for preclinical renal MRI studies. This includes chapters describing the fundamental principles underlying a variety of renal MRI methods, step-by-step protocols for executing renal MRI studies, and detailed guides for data analysis. This collection will serve as a crucial part of a roadmap toward conducting renal MRI studies in a robust and reproducible way, that will promote the standardization and sharing of data.This chapter is based upon work from the COST Action PARENCHIMA, a community-driven network funded by the European Cooperation in Science and Technology (COST) program of the European Union, which aims to improve the reproducibility and standardization of renal MRI biomarkers.

OriginalsprogEngelsk
TitelPreclicinal MRI of the Kidney
UdgivelsesstedNew York
ForlagSpringer
Udgivelsesår2021
Sider3-23
ISBN (trykt)978-1-0716-0977-4
ISBN (Elektronisk)978-1-0716-0978-1
DOI
StatusUdgivet - 2021
SerietitelMethods in Molecular Biology
Vol/bind2216
ISSN1064-3745

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