Aarhus University Seal / Aarhus Universitets segl

Quantum dot based DNA nanosensors for amplification-free detection of human topoisomerase I

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  • Morten Leth Jepsen, Danmark
  • Alessio Ottaviani, Department of Biology, University of Rome Tor Vergata, Italy., Danmark
  • Birgitta R. Knudsen
  • Yi-Ping Ho, Danmark
We develop a quantum dot based DNA nanosensor specifically targeting the cleavage–religation activity of an essential DNA-modifying enzyme, human topoisomerase I. The assay has shown great promise in biological crude samples and thus is expected to contribute to clinical diagnostics and anti-cancer therapy
OriginalsprogEngelsk
TidsskriftR S C Advances
Vol/bind4
Nummer5
Sider (fra-til)2491-2494
Antal sider4
ISSN2046-2069
DOI
StatusUdgivet - 1 jan. 2014

Se relationer på Aarhus Universitet Citationsformater

ID: 84959795