QTL Analysis and Functional Genomics of Animal Model

Publikation: Bog/antologi/afhandling/rapportPh.d.-afhandlingForskning

In recent years, the use of functional genomics and next-generation sequencing technologies has increased the probability of success in studies of complex properties. The integration of large data sets from association studies, DNA resequencing, gene expression profiles and phenotypic data, for example, has enabled scientists to examine more complex interactions in connection with studies of properties and diseases.

In her PhD project, Leila Farajzadeh integrated different organisational levels in biology, including genotype, phenotype, association studies, transcription profiles and genetic variation in the form of single nucleotide polymorphisms (SNPs) to prioritise candidate genes and pathways involved in mechanisms behind complex properties such as obesity. She successfully used RNA-seq techniques in her studies of global expression profiles, as well as quantitative and qualitative aspects of the transcriptome.

OriginalsprogEngelsk
UdgivelsesstedAU-Foulum
ForlagAarhus University, Faculty of Science and Technology
Antal sider155
ISBN (Trykt)978-87-92936-1
Rekvirerende organGraduate School of Science and Technology
StatusUdgivet - 15 feb. 2013

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