Prophylaxis of thromboembolism during therapy with asparaginase in adults with acute lymphoblastic leukaemia

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

  • Cecilie Utke Rank, Rigshospitalet
  • ,
  • Line Stensig Lynggaard
  • Nina Toft, Rigshospitalet
  • ,
  • Ove Juul Juul Nielsen, Rigshospitalet
  • ,
  • Wendy Stock, University of Chicago
  • ,
  • Bodil Als-Nielsen, The Child and Youth Clinic
  • ,
  • Thomas Leth Frandsen, Rigshospitalet
  • ,
  • Ruta Tuckuviene, Department of Pediatrics, Aalborg Universitet
  • ,
  • Kjeld Schmiegelow, Department of Pediatrics and Adolescent Medicine

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: The primary objective is to assess the efficacy and safety of primary thromboprophylaxis for symptomatic VTE in adults with ALL receiving therapy with asparaginase compared with placebo, mechanical thromboprophylaxis, or no thromboprophylaxis. The secondary objective is to compare the efficacy and safety of different groups of primary systemic antithrombotic prophylaxis in adults with ALL receiving therapy with asparaginase by stratifying the main results per type of drug (heparins, vitamin K antagonists, fondaparinux, DOACs, ATIII substitution).

OriginalsprogEngelsk
ArtikelnummerCD013399
TidsskriftCochrane Database of Systematic Reviews
Nummer9
Antal sider21
ISSN1361-6137
DOI
StatusUdgivet - 2019

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