Prevalence of chronic obstructive pulmonary disease and its associated factors in Nepal: Findings from a Community-based Household Survey

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Prevalence of chronic obstructive pulmonary disease and its associated factors in Nepal : Findings from a Community-based Household Survey. / Adhikari, Tara Ballav; Acharya, Pawan; Högman, Marieann et al.

I: International Journal of Chronic Obstructive Pulmonary Disease, Bind 15, 09.2020, s. 2319-2331.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Adhikari, TB, Acharya, P, Högman, M, Neupane, D, Karki, A, Drews, A, Cooper, BG, Sigsgaard, T & Kallestrup, P 2020, 'Prevalence of chronic obstructive pulmonary disease and its associated factors in Nepal: Findings from a Community-based Household Survey', International Journal of Chronic Obstructive Pulmonary Disease, bind 15, s. 2319-2331. https://doi.org/10.2147/COPD.S268110, https://doi.org/10.2147/COPD.S268110

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MLA

Vancouver

Adhikari TB, Acharya P, Högman M, Neupane D, Karki A, Drews A et al. Prevalence of chronic obstructive pulmonary disease and its associated factors in Nepal: Findings from a Community-based Household Survey. International Journal of Chronic Obstructive Pulmonary Disease. 2020 sep.;15:2319-2331. doi: 10.2147/COPD.S268110, 10.2147/COPD.S268110

Author

Adhikari, Tara Ballav ; Acharya, Pawan ; Högman, Marieann et al. / Prevalence of chronic obstructive pulmonary disease and its associated factors in Nepal : Findings from a Community-based Household Survey. I: International Journal of Chronic Obstructive Pulmonary Disease. 2020 ; Bind 15. s. 2319-2331.

Bibtex

@article{bfb8e94d5a3b41a99a35548f42e2c1b2,
title = "Prevalence of chronic obstructive pulmonary disease and its associated factors in Nepal: Findings from a Community-based Household Survey",
abstract = "Background: Despite chronic obstructive pulmonary disease (COPD) being the commonest non-communicable disease in Nepal, there is limited research evidence estimating the spirometry-based burden of COPD. This study aims to estimate the prevalence of COPD and its correlates through a community-based survey in Pokhara Metropolitan City, a semi-urban area of Western Nepal. Methods: A cross-sectional household survey was conducted among 1459 adults ≥40 years. COPD was defined according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria as a post-bronchodilator ratio of forced expiratory volume in 1st second (FEV1) to forced vital capacity (FVC) <0.70 with the presence of symptoms. COPD was also defined by the lower limit of normal (LLN) threshold – FEV1 /FVC < LLN cut-off values with the presence of symptoms. Study participants were interviewed about sociodemographic and behavioural characteristics and respiratory symptoms. Descriptive statistics and logistic regression analysis were applied. Results: Spirometry reports were acceptable in 1438 participants. The mean age of the participants was 55 (±10) years, and, 54% were female. The prevalence of GOLD-defined COPD was 8.5% (95% CI: 7.1–10.0) and based on the LLN threshold of 5.4% (95% CI: 4.2–6.6). The multivariate logistic regression showed that increasing age, low body mass index, illiterate, current or former smoker, and biomass fuel smoke increased the odds of COPD in both the definitions. Conclusion: COPD is highly prevalent at community level and often underdiagnosed. Strategies aiming at early diagnosis and treatment of COPD, especially for the elderly, illiterate, and reducing exposure to smoking and biomass fuel smoke and childhood lung infection could be effective.",
keywords = "COPD, NCD, Nepal, Prevalence",
author = "Adhikari, {Tara Ballav} and Pawan Acharya and Marieann H{\"o}gman and Dinesh Neupane and Arjun Karki and Arne Drews and Cooper, {Brendan G.} and Torben Sigsgaard and Per Kallestrup",
year = "2020",
month = sep,
doi = "10.2147/COPD.S268110",
language = "English",
volume = "15",
pages = "2319--2331",
journal = "International Journal of Chronic Obstructive Pulmonary Disease",
issn = "1178-2005",
publisher = "Dove Medical Press Ltd.",

}

RIS

TY - JOUR

T1 - Prevalence of chronic obstructive pulmonary disease and its associated factors in Nepal

T2 - Findings from a Community-based Household Survey

AU - Adhikari, Tara Ballav

AU - Acharya, Pawan

AU - Högman, Marieann

AU - Neupane, Dinesh

AU - Karki, Arjun

AU - Drews, Arne

AU - Cooper, Brendan G.

AU - Sigsgaard, Torben

AU - Kallestrup, Per

PY - 2020/9

Y1 - 2020/9

N2 - Background: Despite chronic obstructive pulmonary disease (COPD) being the commonest non-communicable disease in Nepal, there is limited research evidence estimating the spirometry-based burden of COPD. This study aims to estimate the prevalence of COPD and its correlates through a community-based survey in Pokhara Metropolitan City, a semi-urban area of Western Nepal. Methods: A cross-sectional household survey was conducted among 1459 adults ≥40 years. COPD was defined according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria as a post-bronchodilator ratio of forced expiratory volume in 1st second (FEV1) to forced vital capacity (FVC) <0.70 with the presence of symptoms. COPD was also defined by the lower limit of normal (LLN) threshold – FEV1 /FVC < LLN cut-off values with the presence of symptoms. Study participants were interviewed about sociodemographic and behavioural characteristics and respiratory symptoms. Descriptive statistics and logistic regression analysis were applied. Results: Spirometry reports were acceptable in 1438 participants. The mean age of the participants was 55 (±10) years, and, 54% were female. The prevalence of GOLD-defined COPD was 8.5% (95% CI: 7.1–10.0) and based on the LLN threshold of 5.4% (95% CI: 4.2–6.6). The multivariate logistic regression showed that increasing age, low body mass index, illiterate, current or former smoker, and biomass fuel smoke increased the odds of COPD in both the definitions. Conclusion: COPD is highly prevalent at community level and often underdiagnosed. Strategies aiming at early diagnosis and treatment of COPD, especially for the elderly, illiterate, and reducing exposure to smoking and biomass fuel smoke and childhood lung infection could be effective.

AB - Background: Despite chronic obstructive pulmonary disease (COPD) being the commonest non-communicable disease in Nepal, there is limited research evidence estimating the spirometry-based burden of COPD. This study aims to estimate the prevalence of COPD and its correlates through a community-based survey in Pokhara Metropolitan City, a semi-urban area of Western Nepal. Methods: A cross-sectional household survey was conducted among 1459 adults ≥40 years. COPD was defined according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria as a post-bronchodilator ratio of forced expiratory volume in 1st second (FEV1) to forced vital capacity (FVC) <0.70 with the presence of symptoms. COPD was also defined by the lower limit of normal (LLN) threshold – FEV1 /FVC < LLN cut-off values with the presence of symptoms. Study participants were interviewed about sociodemographic and behavioural characteristics and respiratory symptoms. Descriptive statistics and logistic regression analysis were applied. Results: Spirometry reports were acceptable in 1438 participants. The mean age of the participants was 55 (±10) years, and, 54% were female. The prevalence of GOLD-defined COPD was 8.5% (95% CI: 7.1–10.0) and based on the LLN threshold of 5.4% (95% CI: 4.2–6.6). The multivariate logistic regression showed that increasing age, low body mass index, illiterate, current or former smoker, and biomass fuel smoke increased the odds of COPD in both the definitions. Conclusion: COPD is highly prevalent at community level and often underdiagnosed. Strategies aiming at early diagnosis and treatment of COPD, especially for the elderly, illiterate, and reducing exposure to smoking and biomass fuel smoke and childhood lung infection could be effective.

KW - COPD

KW - NCD

KW - Nepal

KW - Prevalence

U2 - 10.2147/COPD.S268110

DO - 10.2147/COPD.S268110

M3 - Journal article

C2 - 33061350

AN - SCOPUS:85091797756

VL - 15

SP - 2319

EP - 2331

JO - International Journal of Chronic Obstructive Pulmonary Disease

JF - International Journal of Chronic Obstructive Pulmonary Disease

SN - 1178-2005

ER -