TY - JOUR
T1 - Prepregnancy and Gestational Interventions to Prevent Childhood Obesity
AU - Kampmann, Ulla
AU - Suder, Louise Birk
AU - Nygaard, Malene
AU - Geiker, Nina Rica Wium
AU - Nielsen, Henriette Svarre
AU - Almstrup, Kristian
AU - Bruun, Jens Meldgaard
AU - Magkos, Faidon
AU - Ovesen, Per
AU - Catalano, Patrick
N1 - © The Author(s) 2024. Published by Oxford University Press on behalf of the Endocrine Society. All rights reserved. For commercial re-use, please contact [email protected] for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. See the journal About page for additional terms.
PY - 2024/12/18
Y1 - 2024/12/18
N2 - Childhood obesity is a significant global health issue with complex and multifactorial origins, often beginning before conception and influenced by both maternal and paternal health. The increased prevalence of prepregnancy obesity and gestational diabetes mellitus in women of reproductive age contributes to a heightened risk of metabolic dysfunction in offspring. Current clinical practices often implement lifestyle interventions after the first trimester and have limited success, implying that they miss a critical window for effective metabolic adjustments. This review examines the limitations of lifestyle interventions during pregnancy in improving perinatal outcomes and highlights the importance of initiating such interventions before conception to positively impact parental health and fetal development. A re-evaluation of strategies is needed to enhance the metabolic health of prospective parents as a preventive measure against childhood obesity.
AB - Childhood obesity is a significant global health issue with complex and multifactorial origins, often beginning before conception and influenced by both maternal and paternal health. The increased prevalence of prepregnancy obesity and gestational diabetes mellitus in women of reproductive age contributes to a heightened risk of metabolic dysfunction in offspring. Current clinical practices often implement lifestyle interventions after the first trimester and have limited success, implying that they miss a critical window for effective metabolic adjustments. This review examines the limitations of lifestyle interventions during pregnancy in improving perinatal outcomes and highlights the importance of initiating such interventions before conception to positively impact parental health and fetal development. A re-evaluation of strategies is needed to enhance the metabolic health of prospective parents as a preventive measure against childhood obesity.
KW - Child
KW - Diabetes, Gestational/prevention & control
KW - Female
KW - Humans
KW - Life Style
KW - Pediatric Obesity/prevention & control
KW - Preconception Care/methods
KW - Pregnancy
KW - Pregnancy Complications/prevention & control
KW - Prenatal Care/methods
KW - prepregnancy interventions
KW - lifestyle interventions
KW - metabolic health
KW - gestational diabetes
KW - childhood obesity
UR - http://www.scopus.com/inward/record.url?scp=85213490713&partnerID=8YFLogxK
U2 - 10.1210/clinem/dgae724
DO - 10.1210/clinem/dgae724
M3 - Review
C2 - 39401333
SN - 0021-972X
VL - 110
SP - e8-e18
JO - The Journal of clinical endocrinology and metabolism
JF - The Journal of clinical endocrinology and metabolism
IS - 1
ER -