Preoperative localization of water clear cell giant parathyroid adenoma: A case report

Farid Gossili; Simona Gauduseviciene; Daiva Erentaite; Peter Iversen; Charlotte E. Almasi

doi:10.1016/j.radcr.2024.03.026

Preoperative localization of water clear cell giant parathyroid adenoma: A case report

Farid Gossili^*, Simona Gauduseviciene, Daiva Erentaite, Peter Iversen, Charlotte E. Almasi

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

Abstract

Primary hyperparathyroidism commonly results from a solitary parathyroid adenoma. A water clear cell parathyroid adenoma represents a rare histological variant. This report presents the challenges of preoperative detection of a giant parathyroid adenoma, which was of the water clear cell variant. A case of severe hypercalcemia in a patient without clinical symptoms and equivocal findings on standard imaging modalities, in which the use of [¹¹C]C-Methionine PET/CT facilitated the preoperative detection of a giant parathyroid adenoma. Histopathological examination confirmed the diagnosis of a water clear cell giant parathyroid adenoma following surgical excision. These findings highlight the significance of advanced imaging techniques in the detection and management of a rare form of parathyroid adenoma.

Originalsprog	Engelsk
Tidsskrift	Radiology Case Reports
Vol/bind	19
Nummer	6
Sider (fra-til)	2492-2497
Antal sider	6
ISSN	1930-0433
DOI	https://doi.org/10.1016/j.radcr.2024.03.026
Status	Udgivet - jun. 2024

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10.1016/j.radcr.2024.03.026Licens: CC BY-NC-ND

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title = "Preoperative localization of water clear cell giant parathyroid adenoma: A case report",

abstract = "Primary hyperparathyroidism commonly results from a solitary parathyroid adenoma. A water clear cell parathyroid adenoma represents a rare histological variant. This report presents the challenges of preoperative detection of a giant parathyroid adenoma, which was of the water clear cell variant. A case of severe hypercalcemia in a patient without clinical symptoms and equivocal findings on standard imaging modalities, in which the use of [11C]C-Methionine PET/CT facilitated the preoperative detection of a giant parathyroid adenoma. Histopathological examination confirmed the diagnosis of a water clear cell giant parathyroid adenoma following surgical excision. These findings highlight the significance of advanced imaging techniques in the detection and management of a rare form of parathyroid adenoma.",

keywords = "Giant parathyroid adenoma, Water clear cell, [C]C-Methionine PET/CT",

author = "Farid Gossili and Simona Gauduseviciene and Daiva Erentaite and Peter Iversen and Almasi, {Charlotte E.}",

note = "Publisher Copyright: {\textcopyright} 2024",

year = "2024",

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doi = "10.1016/j.radcr.2024.03.026",

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AU - Gossili, Farid

AU - Gauduseviciene, Simona

AU - Erentaite, Daiva

AU - Iversen, Peter

AU - Almasi, Charlotte E.

PY - 2024/6

Y1 - 2024/6

N2 - Primary hyperparathyroidism commonly results from a solitary parathyroid adenoma. A water clear cell parathyroid adenoma represents a rare histological variant. This report presents the challenges of preoperative detection of a giant parathyroid adenoma, which was of the water clear cell variant. A case of severe hypercalcemia in a patient without clinical symptoms and equivocal findings on standard imaging modalities, in which the use of [11C]C-Methionine PET/CT facilitated the preoperative detection of a giant parathyroid adenoma. Histopathological examination confirmed the diagnosis of a water clear cell giant parathyroid adenoma following surgical excision. These findings highlight the significance of advanced imaging techniques in the detection and management of a rare form of parathyroid adenoma.

AB - Primary hyperparathyroidism commonly results from a solitary parathyroid adenoma. A water clear cell parathyroid adenoma represents a rare histological variant. This report presents the challenges of preoperative detection of a giant parathyroid adenoma, which was of the water clear cell variant. A case of severe hypercalcemia in a patient without clinical symptoms and equivocal findings on standard imaging modalities, in which the use of [11C]C-Methionine PET/CT facilitated the preoperative detection of a giant parathyroid adenoma. Histopathological examination confirmed the diagnosis of a water clear cell giant parathyroid adenoma following surgical excision. These findings highlight the significance of advanced imaging techniques in the detection and management of a rare form of parathyroid adenoma.

KW - Giant parathyroid adenoma

KW - Water clear cell

KW - [C]C-Methionine PET/CT

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DO - 10.1016/j.radcr.2024.03.026

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SN - 1930-0433

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SP - 2492

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JO - Radiology Case Reports

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Preoperative localization of water clear cell giant parathyroid adenoma: A case report

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