Practical guidelines of the EOTTD for pathological and genetic diagnosis of hydatidiform moles

Carla Bartosch*, Alfons Nadal, Ana C. Braga, Angela Salerno, Anne Laure Rougemont, Anne Sophie Van Rompuy, Brendan Fitzgerald, Caroline Joyce, Fabienne Allias, Geoffrey J. Maher, Gitta Turowski, Jean Christophe Tille, Kinan Drak Alsibai, Koen Van de Vijver, Lesley McMahon, Lone Sunde, Michal Pyzlak, Paul Downey, Sandra Wessman, Sophie PatrierBaljeet Kaur, Rosemary Fisher

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisReviewForskningpeer review

3 Citationer (Scopus)

Abstract

Hydatidiform moles are rare and thus most pathologists and geneticists have little experience with their diagnosis. It is important to promptly and correctly identify hydatidiform moles given that they are premalignant disorders associated with a risk of persistent gestational trophoblastic disease and gestational trophoblastic neoplasia. Improvement in diagnosis can be achieved with uniformization of diagnostic criteria and establishment of algorithms. To this aim, the Pathology and Genetics Working Party of the European Organisation for Treatment of Trophoblastic Diseases has developed guidelines that describe the pathological criteria and ancillary techniques that can be used in the differential diagnosis of hydatidiform moles. These guidelines are based on the best available evidence in the literature, professional experience and consensus of the experts’ group involved in its development.

OriginalsprogEngelsk
TidsskriftVirchows Archiv
Vol/bind484
Nummer3
Sider (fra-til)401-422
Antal sider22
ISSN0945-6317
DOI
StatusUdgivet - mar. 2024

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