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Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44

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MASP-1 is the first protein in the activation of the lectin pathway and MASP-1 is, like its isoforms MASP-3 and MAp44, encoded by the MASP1 gene. Our aim was to explore associations between polymorphisms in MASP1 and corresponding concentrations of MASP-1, MASP-3, and MAp44 in plasma as well as the genetic contribution to the equilibrium between the three proteins.
OriginalsprogEngelsk
TidsskriftPLOS ONE
Vol/bind8
Nummer9
Sider (fra-til)e73317
ISSN1932-6203
DOI
StatusUdgivet - 2013

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