Plaque Rupture: Pathoanatomical and Biomechanical Considerations

TY - CHAP

T1 - Plaque Rupture

T2 - Pathoanatomical and Biomechanical Considerations

AU - Frøbert, Ole

N1 - Publisher Copyright: © 2004 by Taylor & Francis Group, LLC.

PY - 2004/1/1

Y1 - 2004/1/1

N2 - Atherosclerosis in the coronary arteries is a very common autopsy finding, even in people not suffering from ischemic heart disease [1]. Although ischemic heart disease is the leading cause of death in the industrialized countries [2], more persons live with coronary atherosclerosis than die of it. Therefore, the key question is not why atherosclerosis develops but, rather, why a quiescent atherosclerotic plaque, after years of indolent growth, suddenly ruptures and becomes highly thrombogenic-the life-threatening event responsible for the great majority of the acute coronary syndromes (ACS)[3,4].

AB - Atherosclerosis in the coronary arteries is a very common autopsy finding, even in people not suffering from ischemic heart disease [1]. Although ischemic heart disease is the leading cause of death in the industrialized countries [2], more persons live with coronary atherosclerosis than die of it. Therefore, the key question is not why atherosclerosis develops but, rather, why a quiescent atherosclerotic plaque, after years of indolent growth, suddenly ruptures and becomes highly thrombogenic-the life-threatening event responsible for the great majority of the acute coronary syndromes (ACS)[3,4].

UR - http://www.scopus.com/inward/record.url?scp=85178590264&partnerID=8YFLogxK

U2 - 10.3109/9780203025673-5

DO - 10.3109/9780203025673-5

M3 - Book chapter

AN - SCOPUS:85178590264

SN - 9780824757953

SP - 59

EP - 76

BT - Acute Coronary Syndromes, Third Edition

PB - CRC Press

ER -