Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Immunocompromised Host Displaying Treatment Induced Viral Evolution

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Standard

Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Immunocompromised Host Displaying Treatment Induced Viral Evolution. / Monrad, Ida; Sahlertz, Signe Risgaard; Nielsen, Stine Sofie Frank et al.

I: Open Forum Infectious Diseases, Bind 8, Nr. 7, ofab295, 07.2021.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

APA

CBE

MLA

Vancouver

Author

Bibtex

@article{64ee7982b72f490296e31632d35fd4e7,
title = "Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Immunocompromised Host Displaying Treatment Induced Viral Evolution",
abstract = "We report a coronavirus disease 2019 case with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) persisting beyond 333 days in an immunocompromised patient with chronic lymphocytic leukemia, asymptomatically carrying infectious SARS-CoV-2 at day 197 postdiagnosis. In addition, viral sequencing indicates major changes in the spike protein over time, temporally associated with convalescent plasma treatment. ",
keywords = "CLL, persistent infection, SARS-CoV-2, viral evolution",
author = "Ida Monrad and Sahlertz, {Signe Risgaard} and Nielsen, {Stine Sofie Frank} and Pedersen, {Louise {\O}rnskov} and Petersen, {Mikkel Steen} and Kobel, {Carl Mathias} and Tarpgaard, {Irene Harder} and Merete Storgaard and Mortensen, {Klaus Leth} and Schleimann, {Mariane H.} and Martin Tolstrup and Vibholm, {Line K.}",
note = "Publisher Copyright: {\textcopyright} 2021 The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.",
year = "2021",
month = jul,
doi = "10.1093/ofid/ofab295",
language = "English",
volume = "8",
journal = "Open Forum Infectious Diseases",
issn = "2328-8957",
publisher = "Oxford University Press",
number = "7",

}

RIS

TY - JOUR

T1 - Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Immunocompromised Host Displaying Treatment Induced Viral Evolution

AU - Monrad, Ida

AU - Sahlertz, Signe Risgaard

AU - Nielsen, Stine Sofie Frank

AU - Pedersen, Louise Ørnskov

AU - Petersen, Mikkel Steen

AU - Kobel, Carl Mathias

AU - Tarpgaard, Irene Harder

AU - Storgaard, Merete

AU - Mortensen, Klaus Leth

AU - Schleimann, Mariane H.

AU - Tolstrup, Martin

AU - Vibholm, Line K.

N1 - Publisher Copyright: © 2021 The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

PY - 2021/7

Y1 - 2021/7

N2 - We report a coronavirus disease 2019 case with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) persisting beyond 333 days in an immunocompromised patient with chronic lymphocytic leukemia, asymptomatically carrying infectious SARS-CoV-2 at day 197 postdiagnosis. In addition, viral sequencing indicates major changes in the spike protein over time, temporally associated with convalescent plasma treatment.

AB - We report a coronavirus disease 2019 case with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) persisting beyond 333 days in an immunocompromised patient with chronic lymphocytic leukemia, asymptomatically carrying infectious SARS-CoV-2 at day 197 postdiagnosis. In addition, viral sequencing indicates major changes in the spike protein over time, temporally associated with convalescent plasma treatment.

KW - CLL

KW - persistent infection

KW - SARS-CoV-2

KW - viral evolution

UR - http://www.scopus.com/inward/record.url?scp=85112495039&partnerID=8YFLogxK

U2 - 10.1093/ofid/ofab295

DO - 10.1093/ofid/ofab295

M3 - Journal article

C2 - 34258320

AN - SCOPUS:85112495039

VL - 8

JO - Open Forum Infectious Diseases

JF - Open Forum Infectious Diseases

SN - 2328-8957

IS - 7

M1 - ofab295

ER -