Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Immunocompromised Host Displaying Treatment Induced Viral Evolution

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We report a coronavirus disease 2019 case with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) persisting beyond 333 days in an immunocompromised patient with chronic lymphocytic leukemia, asymptomatically carrying infectious SARS-CoV-2 at day 197 postdiagnosis. In addition, viral sequencing indicates major changes in the spike protein over time, temporally associated with convalescent plasma treatment.

OriginalsprogEngelsk
Artikelnummerofab295
TidsskriftOpen Forum Infectious Diseases
Vol/bind8
Nummer7
Antal sider5
ISSN2328-8957
DOI
StatusUdgivet - jul. 2021

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