Paraganglioma of the head and neck region, treated with radiation therapy, a Rare Cancer Network study

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

DOI

  • Yasmin Lassen-Ramshad
  • Enis Ozyar, Acibadem M.A. Aydinlar University, School of Medicine, Department of Radiation Oncology, Turkey.
  • ,
  • Senem Alanyali, Department of Radiation Oncology, Faculty of Medicine, Ege University, Turkey.
  • ,
  • Philip Poortmans, Radiation Oncology Department, Institut Curie, Paris, France.
  • ,
  • Paul van Houtte, Department of Radiation Oncology, Jules Bordet Institute, Brussels, Belgium.
  • ,
  • Schoeb Sohawon, Department of Radiation Oncology, Jules Bordet Institute, Brussels, Belgium.
  • ,
  • Mustafa Esassolak, Department of Radiation Oncology, Faculty of Medicine, Ege University, Turkey.
  • ,
  • Marco Krengli, Department of Radiotherapy, University of Piemonte Orientale, Novara, Italy.
  • ,
  • Salvador Villa, Department of Radiation Oncology, Catalan Institute of Oncoloy, Badalona, Spain.
  • ,
  • Robert Miller, Department of Radiation Oncology, Mayo Clinic, Jacksonville, FL, USA.
  • ,
  • Candan Demiroz, Uludag University Faculty of Medicine, Radiation Oncology Clinical Division, Turkey.
  • ,
  • Serap Akyurek, Department of Radiotherapy, Ankara University School of Medicine, Ankara, Turkey.
  • ,
  • Ninna Aggerholm-Pedersen
  • Juliette Thariat, Radiation Oncology Department, Centre Francois Baclesse, Caen, France.

BACKGROUND: Paraganglioma of the head and neck (HNPGL) are rare often benign tumors. Surgery and radiation therapy (RT) are the main treatment choices. We present an analysis of outcome and toxicity after RT from 13 institutions of the Rare Cancer Network.

METHODS: Data were collected using a questionnaire concerning patients' characteristics, treatment, and outcome. A total of 81 patients with 82 HNPGL were analyzed.

RESULTS: The median follow-up was 48 months (1-456). Sixty-two lesions were treated with conventional RT and 20 lesions with stereotactic RT. Local control (LC) was achieved in 69 out of 77 lesions. Late toxicity occurred in 17 patients. Patients treated with stereotactic RT experienced neither disease progression nor late toxicity. Four patients with a follow-up longer than 20 years experienced disease progression.

CONCLUSION: RT for HNPGL offered good local control with acceptable toxicity. Stereotactic RT might offer better results. Long-term follow-up is required.

OriginalsprogEngelsk
TidsskriftHead & Neck (Print Edition)
Vol/bind41
Nummer6
Sider (fra-til)1770-1776
Antal sider7
ISSN1043-3074
DOI
StatusUdgivet - jun. 2019

Bibliografisk note

© 2019 Wiley Periodicals, Inc.

Se relationer på Aarhus Universitet Citationsformater

ID: 155215787