Painful and non-painful diabetic polyneuropathy: Clinical characteristics and diagnostic issues

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisReviewForskningpeer review

DOI

  • Sandra Sif Gylfadottir
  • Danita Weeracharoenkul, Chulalongkorn Univ, Chulalongkorn University, King Chulalongkorn Mem Hosp, Pain Management Res Unit, Dept Anesthesiol,Fac Med
  • ,
  • Signe Toft Andersen
  • Supranee Niruthisard, Chulalongkorn Univ, Chulalongkorn University, King Chulalongkorn Mem Hosp, Pain Management Res Unit, Dept Anesthesiol,Fac Med
  • ,
  • Sompongse Suwanwalaikorn, Chulalongkorn Univ, Chulalongkorn University, King Chulalongkorn Mem Hosp, Fac Med, Dept Med
  • ,
  • Troels Staehelin Jensen

Diabetic neuropathy (DN) is a common complication of diabetes and can be either painful or non-painful. It is challenging to diagnose this complication, as no biomarker or clear consensus on the clinical definition of either painful or non-painful DN exists. Hence, a hierarchical classification has been developed categorizing the probability of the diagnosis into: possible, probable or definite, based on the clinical presentation of symptoms and signs. Pain is a warning signal of tissue damage, and non-painful DN therefore represents a clinical and diagnostic challenge because it often goes unnoticed until irreversible nerve damage has occurred. Simple clinical tests seem to be the best for evaluation of DN in the general care for diabetes. Screening programs at regular intervals might be the most optimal strategy for early detection and interventions to possibly prevent further neuronal damage and to lower the economic burden of this complication.

OriginalsprogEngelsk
TidsskriftJournal of Diabetes Investigation
Vol/bind10
Nummer5
Sider (fra-til)1148-1157
Antal sider10
ISSN2040-1116
DOI
StatusUdgivet - sep. 2019

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