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p53 and PPP1R13L (alias iASPP or RAI) form a feedback loop to regulate genotoxic stress responses

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  • Institut for Human Genetik
  • Afdeling for Miljø- og Arbejdsmedicin
PPP1R13L gene has been found to be over-expressed in variety of cancers and its expression in p53 wild-type background is sufficient to promote tumor growth in vivo. However, in the non-transformed cells it acts as a tumor suppressor which suggests that the role of PPP1R13L is multifaceted.
OriginalsprogEngelsk
TidsskriftBBA General Subjects
Vol/bind1800
Nummer12
Sider (fra-til)1231-40
Antal sider10
ISSN0304-4165
DOI
StatusUdgivet - 1 dec. 2010

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