Outcomes among non-Western immigrant patients and Danish-born patients with acute myeloid Leukaemia: A Danish population-based cohort study

TY - JOUR

T1 - Outcomes among non-Western immigrant patients and Danish-born patients with acute myeloid Leukaemia

T2 - A Danish population-based cohort study

AU - Kristensen, Daniel Tuyet

AU - Simonsen, Mikkel Runason

AU - Roug, Anne Stidsholt

AU - Marcher, Claus Werenberg

AU - Ørskov, Andreas Due

AU - Sørensen, Anne Louise Tøllbøll

AU - El-Galaly, Tarec Christoffer

AU - Baech, Joachim

N1 - © 2024 The Author(s). British Journal of Haematology published by British Society for Haematology and John Wiley & Sons Ltd.

PY - 2024/10/22

Y1 - 2024/10/22

N2 - Non-Western immigrant patients (NWIPs) may be a vulnerable population when diagnosed and treated for acute myeloid leukaemia (AML). Here we report selected quality parameters related to diagnosis, treatment, and outcome of newly diagnosed AML among NWIPs (n = 119) and Danish-born patients (DBPs) (n = 4689). No adjusted differences were observed for time-to-diagnosis, time-to-treatment, treatment allocation, rates of complete remission, early death, allogeneic stem cell transplantation, and overall survival between NWIPs and DBPs. Among patients allocated for intensive chemotherapy, NWIPs were less likely to participate in clinical trials. The findings highlight equitable AML care but underscore the need to enhance NWIP participation in clinical trials.

AB - Non-Western immigrant patients (NWIPs) may be a vulnerable population when diagnosed and treated for acute myeloid leukaemia (AML). Here we report selected quality parameters related to diagnosis, treatment, and outcome of newly diagnosed AML among NWIPs (n = 119) and Danish-born patients (DBPs) (n = 4689). No adjusted differences were observed for time-to-diagnosis, time-to-treatment, treatment allocation, rates of complete remission, early death, allogeneic stem cell transplantation, and overall survival between NWIPs and DBPs. Among patients allocated for intensive chemotherapy, NWIPs were less likely to participate in clinical trials. The findings highlight equitable AML care but underscore the need to enhance NWIP participation in clinical trials.

KW - acute myeloid leukaemia

KW - clinical outcome

KW - clinical trial participation

KW - immigrant patients

KW - non-western immigrants

UR - http://www.scopus.com/inward/record.url?scp=85207315706&partnerID=8YFLogxK

U2 - 10.1111/bjh.19850

DO - 10.1111/bjh.19850

M3 - Journal article

C2 - 39439197

SN - 0007-1048

JO - British Journal of Haematology

JF - British Journal of Haematology

ER -