Orofacial Symptoms and Oral-Health-Related Quality of Life in JIA: A two-year observational follow-up study

TY - ABST

T1 - Orofacial Symptoms and Oral-Health-Related Quality of Life in JIA: A two-year observational follow-up study

AU - Rahimi, Hanna

AU - Twilt, Marinka

AU - Spiegel, Lynn

AU - Herlin, Troels

AU - Koos, Bernd

AU - Küseler, Annelise

AU - Pedersen, Thomas Klit

AU - Stoustrup, Peter Bangsgaard

PY - 2017/9/14

Y1 - 2017/9/14

N2 - PReS 2017 Abstract Submission Topic: JIA (oligo, poly, psoriatic) PReS-ABS-1339 OROFACIAL SYMPTOMS AND ORAL HEALTH-RELATED QUALITY OF LIFE IN JIA: A TWO-YEAR OBSERVATIONAL FOLLOW-UP STUDY H. Rahimi* 1, M. Twilt2, L. Spiegel3, T. Herlin1, B. Koos4, A. Küseler5, T. K. Pedersen1, P. Stoustrup5 1Aarhus University Hospital, Århus, Denmark, 2Alberta Children’s Hospital, Calgary, 3The Hospital for Sick Children, Toronto, Canada, 4University of Tübingen, Tübingen, Germany, 5Aarhus University, Århus, Denmark What is your preferred presentation method?: Oral or Poster I would like to submit this abstract for:: PReS Congress and Young Investigator Meeting Please indicate your date of birth: 14.05.1992 Introduction: Orofacial symptoms are common findings in patients with juvenile idiopathic arthritis (JIA). However, little is known about the chronicity of orofacial symptoms and how this influences the oral health-related quality of life (OHRQOL) in patients with JIA. Objectives: 1) To study the long-term changes in self-reported orofacial symptoms, 2) To define the impact of orofacial symptoms on OHRQOL. Methods: Consecutive patients were invited to participate in this study. Inclusion criteria were: 1) JIA diagnosis, 2) ≤20 years of age. At baseline (T0), the patients completed the euroTMjoint patient questionnaire that incorporates six domains related to the orofacial area. Among others, pain frequency was assessed using a 5 point Likert scale (0=”Never”, 1=”Less than once a week”, 2=”Several times a week”, 3=”Several times a day”, 4=”All the time”). A 100 mm VAS was used to assess orofacial functional disability (0=”Not affected”, 100=”Severely affected”). At follow-up (T1), the patients completed the same items of the baseline questionnaire in addition to a validated 31-item questionnaire addressing OHRQOL, including global ratings of self-reported perception of oral health (5 point Likert scale, “Excellent”=0 to “Poor”=4), and the extent to which the orofacial conditions affected the overall well-being and general quality of life (5 point Likert scale, 0=”Not at all”, 4=”Very much”). Results: At baseline, 157 consecutive patients completed the questionnaire. At the two-year follow-up (mean 24 months, SD 3.2 months), 111 patients repeated the questionnaire (response rate 71%). Only patients who completed the questionnaires at both time points were included in the analysis. Baseline (T0): 53% (59/111) of the patients reported a presence of orofacial pain, and 36% (40/111) of the patients reported a disabled orofacial function. Baseline findings of excluded non-responders (n=46) were comparable to the included group of patients. Follow-up (T1): 76% (45/59) of the patients with orofacial pain at T0 still reported pain at T1. Changes were as follows: 29% (13/45) had less frequent pain, 40% (18/45) had comparable pain frequency, and 31% (14/45) had more frequent pain at T1. 65% (26/40) of the patients with orofacial functional disability at T0 also reported disability at T1. Changes were as follows: 27% (7/26) reported an improvement of orofacial functional disability, 42% (11/26) reported the same level of orofacial functional disability, and 31% (8/26) reported a worsening of orofacial functional disability at T1. Global ratings of self-reported perception of oral health, and the extent to which the orofacial conditions affected the overall wellbeing and general quality of life were significantly reduced in patients in pain (p<0.0001) compared to asymptomatic patients. 16% (10/61) of the patients with orofacial pain and/or functional disability reported that the condition had “Some” (Likert scale score 2) negative impact on the overall quality of life. 7% (4/61) reported that the orofacial condition reduced general quality of life “A lot” (1/61, score 3) and “Very much” (3/61, score 4). Conclusion: This study shows: 1) Self-reported orofacial pain and functional disability were common findings in a cohort of JIA patients followed over two years. 2) These symptoms seem to persist over time in most patients. 3) Orofacial pain and functional disability significantly reduce OHRQOL. 4) General quality of life is substantially affected in 23% of the patients with orofacial symptoms. Disclosure of Interest: None Declared

AB - PReS 2017 Abstract Submission Topic: JIA (oligo, poly, psoriatic) PReS-ABS-1339 OROFACIAL SYMPTOMS AND ORAL HEALTH-RELATED QUALITY OF LIFE IN JIA: A TWO-YEAR OBSERVATIONAL FOLLOW-UP STUDY H. Rahimi* 1, M. Twilt2, L. Spiegel3, T. Herlin1, B. Koos4, A. Küseler5, T. K. Pedersen1, P. Stoustrup5 1Aarhus University Hospital, Århus, Denmark, 2Alberta Children’s Hospital, Calgary, 3The Hospital for Sick Children, Toronto, Canada, 4University of Tübingen, Tübingen, Germany, 5Aarhus University, Århus, Denmark What is your preferred presentation method?: Oral or Poster I would like to submit this abstract for:: PReS Congress and Young Investigator Meeting Please indicate your date of birth: 14.05.1992 Introduction: Orofacial symptoms are common findings in patients with juvenile idiopathic arthritis (JIA). However, little is known about the chronicity of orofacial symptoms and how this influences the oral health-related quality of life (OHRQOL) in patients with JIA. Objectives: 1) To study the long-term changes in self-reported orofacial symptoms, 2) To define the impact of orofacial symptoms on OHRQOL. Methods: Consecutive patients were invited to participate in this study. Inclusion criteria were: 1) JIA diagnosis, 2) ≤20 years of age. At baseline (T0), the patients completed the euroTMjoint patient questionnaire that incorporates six domains related to the orofacial area. Among others, pain frequency was assessed using a 5 point Likert scale (0=”Never”, 1=”Less than once a week”, 2=”Several times a week”, 3=”Several times a day”, 4=”All the time”). A 100 mm VAS was used to assess orofacial functional disability (0=”Not affected”, 100=”Severely affected”). At follow-up (T1), the patients completed the same items of the baseline questionnaire in addition to a validated 31-item questionnaire addressing OHRQOL, including global ratings of self-reported perception of oral health (5 point Likert scale, “Excellent”=0 to “Poor”=4), and the extent to which the orofacial conditions affected the overall well-being and general quality of life (5 point Likert scale, 0=”Not at all”, 4=”Very much”). Results: At baseline, 157 consecutive patients completed the questionnaire. At the two-year follow-up (mean 24 months, SD 3.2 months), 111 patients repeated the questionnaire (response rate 71%). Only patients who completed the questionnaires at both time points were included in the analysis. Baseline (T0): 53% (59/111) of the patients reported a presence of orofacial pain, and 36% (40/111) of the patients reported a disabled orofacial function. Baseline findings of excluded non-responders (n=46) were comparable to the included group of patients. Follow-up (T1): 76% (45/59) of the patients with orofacial pain at T0 still reported pain at T1. Changes were as follows: 29% (13/45) had less frequent pain, 40% (18/45) had comparable pain frequency, and 31% (14/45) had more frequent pain at T1. 65% (26/40) of the patients with orofacial functional disability at T0 also reported disability at T1. Changes were as follows: 27% (7/26) reported an improvement of orofacial functional disability, 42% (11/26) reported the same level of orofacial functional disability, and 31% (8/26) reported a worsening of orofacial functional disability at T1. Global ratings of self-reported perception of oral health, and the extent to which the orofacial conditions affected the overall wellbeing and general quality of life were significantly reduced in patients in pain (p<0.0001) compared to asymptomatic patients. 16% (10/61) of the patients with orofacial pain and/or functional disability reported that the condition had “Some” (Likert scale score 2) negative impact on the overall quality of life. 7% (4/61) reported that the orofacial condition reduced general quality of life “A lot” (1/61, score 3) and “Very much” (3/61, score 4). Conclusion: This study shows: 1) Self-reported orofacial pain and functional disability were common findings in a cohort of JIA patients followed over two years. 2) These symptoms seem to persist over time in most patients. 3) Orofacial pain and functional disability significantly reduce OHRQOL. 4) General quality of life is substantially affected in 23% of the patients with orofacial symptoms. Disclosure of Interest: None Declared

UR - http://www.pres.eu/pres2017/networking-activities.html

M3 - Conference abstract in journal

SN - 1546-0096

VL - 15

JO - Pediatric Rheumatology

JF - Pediatric Rheumatology

IS - Supplement 2:65

M1 - P236

T2 - 24th European Paediatric Rheumatology Congress

Y2 - 14 September 2017 through 17 September 2017

ER -