Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation

Mariam Abdi Noor; Leila Louise Benhassen; Alexander Emil Kaspersen; Marc Gjern Weiss; John Michael Hasenkam; Peter Johansen

doi:10.1007/s12265-023-10393-7

Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation

Mariam Abdi Noor^*, Leila Louise Benhassen, Alexander Emil Kaspersen, Marc Gjern Weiss, John Michael Hasenkam, Peter Johansen

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

2 Citationer (Scopus)

4 Downloads (Pure)

Abstract

An increasing body of research indicates that annular stability plays a key role for a successful aortic valve repair. The aim of this study was to evaluate and compare a novel open aortic annuloplasty ring (the A-ring) with the Dacron ring. Both rings were compared with native aortic roots in vitro. Eighteen aortic roots were included in the study and randomized into three groups: the native, Dacron, and A-ring group. The roots were evaluated in an in vitro physiologic pulsatile model simulating the left side of the heart. Aortic annulus diameters were significantly reduced both in the Dacron ring group (p = 0.003) and the A-ring group (p = 0.020) when compared with the native group. Both the Dacron ring and A-ring effectively downsized the aortic annulus diameter. The A-ring also displayed an ability to maintain aortic root distensibility during the cardiac cycle equally to the Dacron ring. Graphical abstract: [Figure not available: see fulltext.]

Originalsprog	Engelsk
Tidsskrift	Journal of Cardiovascular Translational Research
Vol/bind	16
Nummer	5
Sider (fra-til)	1144-1152
Antal sider	9
ISSN	1937-5387
DOI	https://doi.org/10.1007/s12265-023-10393-7
Status	Udgivet - okt. 2023

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10.1007/s12265-023-10393-7Licens: CC BY

s12265-023-10393-7Forlagets udgivne version, 1,03 MBLicens: CC BY

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title = "Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation",

abstract = "An increasing body of research indicates that annular stability plays a key role for a successful aortic valve repair. The aim of this study was to evaluate and compare a novel open aortic annuloplasty ring (the A-ring) with the Dacron ring. Both rings were compared with native aortic roots in vitro. Eighteen aortic roots were included in the study and randomized into three groups: the native, Dacron, and A-ring group. The roots were evaluated in an in vitro physiologic pulsatile model simulating the left side of the heart. Aortic annulus diameters were significantly reduced both in the Dacron ring group (p = 0.003) and the A-ring group (p = 0.020) when compared with the native group. Both the Dacron ring and A-ring effectively downsized the aortic annulus diameter. The A-ring also displayed an ability to maintain aortic root distensibility during the cardiac cycle equally to the Dacron ring. Graphical abstract: [Figure not available: see fulltext.]",

keywords = "Annuloplasty, Aortic valve repair, Cardiovascular interventions, Hemodynamics, Polyethylene Terephthalates, Humans, Heart Valve Prosthesis, Aortic Valve Insufficiency, Prosthesis Design, Aortic Valve/diagnostic imaging, Cardiac Valve Annuloplasty/adverse effects",

author = "Noor, {Mariam Abdi} and Benhassen, {Leila Louise} and Kaspersen, {Alexander Emil} and Weiss, {Marc Gjern} and Hasenkam, {John Michael} and Peter Johansen",

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doi = "10.1007/s12265-023-10393-7",

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Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation. / Noor, Mariam Abdi ; Benhassen, Leila Louise ; Kaspersen, Alexander Emil et al.
I: Journal of Cardiovascular Translational Research, Bind 16, Nr. 5, 10.2023, s. 1144-1152.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

TY - JOUR

T1 - Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation

AU - Noor, Mariam Abdi

AU - Benhassen, Leila Louise

AU - Kaspersen, Alexander Emil

AU - Weiss, Marc Gjern

AU - Hasenkam, John Michael

AU - Johansen, Peter

PY - 2023/10

Y1 - 2023/10

N2 - An increasing body of research indicates that annular stability plays a key role for a successful aortic valve repair. The aim of this study was to evaluate and compare a novel open aortic annuloplasty ring (the A-ring) with the Dacron ring. Both rings were compared with native aortic roots in vitro. Eighteen aortic roots were included in the study and randomized into three groups: the native, Dacron, and A-ring group. The roots were evaluated in an in vitro physiologic pulsatile model simulating the left side of the heart. Aortic annulus diameters were significantly reduced both in the Dacron ring group (p = 0.003) and the A-ring group (p = 0.020) when compared with the native group. Both the Dacron ring and A-ring effectively downsized the aortic annulus diameter. The A-ring also displayed an ability to maintain aortic root distensibility during the cardiac cycle equally to the Dacron ring. Graphical abstract: [Figure not available: see fulltext.]

AB - An increasing body of research indicates that annular stability plays a key role for a successful aortic valve repair. The aim of this study was to evaluate and compare a novel open aortic annuloplasty ring (the A-ring) with the Dacron ring. Both rings were compared with native aortic roots in vitro. Eighteen aortic roots were included in the study and randomized into three groups: the native, Dacron, and A-ring group. The roots were evaluated in an in vitro physiologic pulsatile model simulating the left side of the heart. Aortic annulus diameters were significantly reduced both in the Dacron ring group (p = 0.003) and the A-ring group (p = 0.020) when compared with the native group. Both the Dacron ring and A-ring effectively downsized the aortic annulus diameter. The A-ring also displayed an ability to maintain aortic root distensibility during the cardiac cycle equally to the Dacron ring. Graphical abstract: [Figure not available: see fulltext.]

KW - Annuloplasty

KW - Aortic valve repair

KW - Cardiovascular interventions

KW - Hemodynamics

KW - Polyethylene Terephthalates

KW - Humans

KW - Heart Valve Prosthesis

KW - Aortic Valve Insufficiency

KW - Prosthesis Design

KW - Aortic Valve/diagnostic imaging

KW - Cardiac Valve Annuloplasty/adverse effects

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U2 - 10.1007/s12265-023-10393-7

DO - 10.1007/s12265-023-10393-7

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AN - SCOPUS:85160848533

SN - 1937-5387

VL - 16

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EP - 1152

JO - Journal of Cardiovascular Translational Research

JF - Journal of Cardiovascular Translational Research

IS - 5

ER -

Novel Expansible Aortic Annuloplasty Ring Exhibits Similar Characteristics as the Dacron Ring—an In Vitro Evaluation

Abstract

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