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Novel Brassinosteroid-Modified Polyethylene Glycol Micelles for Controlled Release of Agrochemicals

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Standard

Novel Brassinosteroid-Modified Polyethylene Glycol Micelles for Controlled Release of Agrochemicals. / Pérez Quiñones, Javier; Brüggemann, Oliver; Kjems, Jørgen; Shahavi, Mohammad Hassan; Peniche Covas, Carlos.

I: Journal of Agricultural and Food Chemistry, Bind 66, Nr. 7, 29.01.2018, s. 1612-1619.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review

Harvard

Pérez Quiñones, J, Brüggemann, O, Kjems, J, Shahavi, MH & Peniche Covas, C 2018, 'Novel Brassinosteroid-Modified Polyethylene Glycol Micelles for Controlled Release of Agrochemicals', Journal of Agricultural and Food Chemistry, bind 66, nr. 7, s. 1612-1619. https://doi.org/10.1021/acs.jafc.7b05019

APA

Pérez Quiñones, J., Brüggemann, O., Kjems, J., Shahavi, M. H., & Peniche Covas, C. (2018). Novel Brassinosteroid-Modified Polyethylene Glycol Micelles for Controlled Release of Agrochemicals. Journal of Agricultural and Food Chemistry, 66(7), 1612-1619. https://doi.org/10.1021/acs.jafc.7b05019

CBE

Pérez Quiñones J, Brüggemann O, Kjems J, Shahavi MH, Peniche Covas C. 2018. Novel Brassinosteroid-Modified Polyethylene Glycol Micelles for Controlled Release of Agrochemicals. Journal of Agricultural and Food Chemistry. 66(7):1612-1619. https://doi.org/10.1021/acs.jafc.7b05019

MLA

Pérez Quiñones, Javier o.a.. "Novel Brassinosteroid-Modified Polyethylene Glycol Micelles for Controlled Release of Agrochemicals". Journal of Agricultural and Food Chemistry. 2018, 66(7). 1612-1619. https://doi.org/10.1021/acs.jafc.7b05019

Vancouver

Pérez Quiñones J, Brüggemann O, Kjems J, Shahavi MH, Peniche Covas C. Novel Brassinosteroid-Modified Polyethylene Glycol Micelles for Controlled Release of Agrochemicals. Journal of Agricultural and Food Chemistry. 2018 jan 29;66(7):1612-1619. https://doi.org/10.1021/acs.jafc.7b05019

Author

Pérez Quiñones, Javier ; Brüggemann, Oliver ; Kjems, Jørgen ; Shahavi, Mohammad Hassan ; Peniche Covas, Carlos. / Novel Brassinosteroid-Modified Polyethylene Glycol Micelles for Controlled Release of Agrochemicals. I: Journal of Agricultural and Food Chemistry. 2018 ; Bind 66, Nr. 7. s. 1612-1619.

Bibtex

@article{747b4d9c457a49af83cc1e07103349b5,
title = "Novel Brassinosteroid-Modified Polyethylene Glycol Micelles for Controlled Release of Agrochemicals",
abstract = "Two synthetic analogues of brassinosteroids (DI31 and S7) exhibit good plant growth enhancer activity. However, their hydrophobicity and quick metabolism in plants have limited their application and benefits in agriculture. Our objective was to prepare novel brassinosteroid-modified polyethylene glycol (PEG) micelles to achieve controlled release with extended stability while retaining agrochemical activity. Spectroscopic studies confirmed quantitative disubstitution of studied PEGs with the brassinosteroids, while elemental analysis assessed purity of the synthesized conjugates. Conjugates were also characterized by X-ray diffraction and thermal analysis. Dynamic and static light scattering showed stable and homogeneous approximately spherical micelles with average hydrodynamic diameters of 22-120 nm and almost neutral ζ potential. Spherical 30-140 nm micelles were observed by electron microscopy. Sustained in vitro releases at pH 5.5 were extended up to 96 h. Prepared PEG micelles showed good agrochemical activity in the radish seed bioassay and no cytotoxicity to the human microvascular endothelial cell line in the MTS test.",
keywords = "agrochemicals, brassinosteroids, controlled release, PEG micelles",
author = "{P{\'e}rez Qui{\~n}ones}, Javier and Oliver Br{\"u}ggemann and J{\o}rgen Kjems and Shahavi, {Mohammad Hassan} and {Peniche Covas}, Carlos",
year = "2018",
month = jan,
day = "29",
doi = "10.1021/acs.jafc.7b05019",
language = "English",
volume = "66",
pages = "1612--1619",
journal = "Journal of Agricultural and Food Chemistry",
issn = "0021-8561",
publisher = "AMER CHEMICAL SOC",
number = "7",

}

RIS

TY - JOUR

T1 - Novel Brassinosteroid-Modified Polyethylene Glycol Micelles for Controlled Release of Agrochemicals

AU - Pérez Quiñones, Javier

AU - Brüggemann, Oliver

AU - Kjems, Jørgen

AU - Shahavi, Mohammad Hassan

AU - Peniche Covas, Carlos

PY - 2018/1/29

Y1 - 2018/1/29

N2 - Two synthetic analogues of brassinosteroids (DI31 and S7) exhibit good plant growth enhancer activity. However, their hydrophobicity and quick metabolism in plants have limited their application and benefits in agriculture. Our objective was to prepare novel brassinosteroid-modified polyethylene glycol (PEG) micelles to achieve controlled release with extended stability while retaining agrochemical activity. Spectroscopic studies confirmed quantitative disubstitution of studied PEGs with the brassinosteroids, while elemental analysis assessed purity of the synthesized conjugates. Conjugates were also characterized by X-ray diffraction and thermal analysis. Dynamic and static light scattering showed stable and homogeneous approximately spherical micelles with average hydrodynamic diameters of 22-120 nm and almost neutral ζ potential. Spherical 30-140 nm micelles were observed by electron microscopy. Sustained in vitro releases at pH 5.5 were extended up to 96 h. Prepared PEG micelles showed good agrochemical activity in the radish seed bioassay and no cytotoxicity to the human microvascular endothelial cell line in the MTS test.

AB - Two synthetic analogues of brassinosteroids (DI31 and S7) exhibit good plant growth enhancer activity. However, their hydrophobicity and quick metabolism in plants have limited their application and benefits in agriculture. Our objective was to prepare novel brassinosteroid-modified polyethylene glycol (PEG) micelles to achieve controlled release with extended stability while retaining agrochemical activity. Spectroscopic studies confirmed quantitative disubstitution of studied PEGs with the brassinosteroids, while elemental analysis assessed purity of the synthesized conjugates. Conjugates were also characterized by X-ray diffraction and thermal analysis. Dynamic and static light scattering showed stable and homogeneous approximately spherical micelles with average hydrodynamic diameters of 22-120 nm and almost neutral ζ potential. Spherical 30-140 nm micelles were observed by electron microscopy. Sustained in vitro releases at pH 5.5 were extended up to 96 h. Prepared PEG micelles showed good agrochemical activity in the radish seed bioassay and no cytotoxicity to the human microvascular endothelial cell line in the MTS test.

KW - agrochemicals

KW - brassinosteroids

KW - controlled release

KW - PEG micelles

UR - http://www.scopus.com/inward/record.url?scp=85042390341&partnerID=8YFLogxK

U2 - 10.1021/acs.jafc.7b05019

DO - 10.1021/acs.jafc.7b05019

M3 - Journal article

C2 - 29378135

AN - SCOPUS:85042390341

VL - 66

SP - 1612

EP - 1619

JO - Journal of Agricultural and Food Chemistry

JF - Journal of Agricultural and Food Chemistry

SN - 0021-8561

IS - 7

ER -