Normative values for gastric motility assessed with the 3D-transit electromagnetic tracking system

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review


  • Nanna Sutter
  • ,
  • Mette Winther Klinge
  • Esben Bolvig Mark, Aalborg Universitet
  • ,
  • Gursharan Nandhra, Queen Mary University of London, The Royal London Hospital
  • ,
  • Anne-Mette Haase
  • Jakob Poulsen, Aalborg Universitet
  • ,
  • Karoline Knudsen
  • ,
  • Per Borghammer
  • Vincent Schlageter, Motilis Medica SA, Lausanne, Switzerland.
  • ,
  • Malcolm Birch, Queen Mary University of London, The Royal London Hospital
  • ,
  • S Mark Scott, Queen Mary University of London
  • ,
  • Asbjørn Mohr Drewes
  • Klaus Krogh

BACKGROUND: The Motilis 3D-Transit system allows ambulatory description of transit patterns throughout the gastrointestinal tract and offers an alternative method for studying gastric motility. We aimed to establish normative values for gastric motility assessed with the method.

METHOD: A total of 132 healthy volunteers ingested the 3D-Transit capsule for assessment of gastrointestinal transit times. Recordings from 125 subjects were used for definition of normative values. Forty-six subjects were studied on two consecutive days. Recordings were reanalyzed using newly developed software providing information on gastric emptying (GE) as well as contraction frequency and movement during gastric contractions.

RESULTS: The median GE time was 2.7 hours (range 0.1-21.2). In 89% of subjects, the capsule passed the pylorus within a postingestion period of 6 hours. The median frequency of gastric contractions was 3.1 per minute (range 2.6-3.8). The frequency was higher in women (3.2, range 2.7-3.8) than in men (3.0, range 2.6-3.5) and increased with age (0.004 per year) (P < .05). The median amplitudes were 35° (range 4-85) when based on rotation of the capsule and 11 mm (range 6-31) when based on capsule change in position. The rotation amplitude was higher in women and decreased with increasing BMI (P < .05). The position amplitude was also higher in women and increased with the amount of calories in the test meal, but decreased with increasing BMI and age (P < .05). Day-to-day variation (P > .05) was considerable while inter-rater variability was small.

CONCLUSION AND INFERENCES: We have established normative values for gastric motility assessed with the 3D-Transit system.

TidsskriftNeurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
Antal sider8
StatusUdgivet - jun. 2020

Se relationer på Aarhus Universitet Citationsformater

ID: 181962390