Næsen kan være fokus for behandling af og profylakse mod COVID-19

Maria Rusan; Thomas Oliver Kamarauskas Ovesen; Kurt Fuursted; Therese Ovesen

Næsen kan være fokus for behandling af og profylakse mod COVID-19

Maria Rusan, Thomas Oliver Kamarauskas Ovesen, Kurt Fuursted, Therese Ovesen^*

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

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Abstract

Infection with SARS-CoV-2 frequently commences in the nasal cavity, yet knowledge about this initial virus-host interaction is sparse. In this review, we update our current understanding of SARS-CoV-2 infection via the nasal epithelium and the associated local immune response. Furthermore, we present considerations to how this interaction may influence the clinical course of COVID-19 and the systemic immune response, and lastly touch upon the potential for intranasal vaccination, intranasal antiviral therapies and immunomodulatory approaches

Bidragets oversatte titel	The nose can be the focus of treatment and prophylactic approaches against COVID-19
Originalsprog	Dansk
Artikelnummer	V05210442
Tidsskrift	Ugeskrift for Læger
Vol/bind	183
Nummer	2
Antal sider	9
ISSN	0041-5782
Status	Udgivet - jan. 2022

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Næsen kan være fokus for behandling af og profylakse mod COVID-19Forlagets udgivne version, 857 KBLicens: CC BY-NC-ND

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AU - Ovesen, Thomas Oliver Kamarauskas

AU - Fuursted, Kurt

AU - Ovesen, Therese

PY - 2022/1

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AB - Infection with SARS-CoV-2 frequently commences in the nasal cavity, yet knowledge about this initial virus-host interaction is sparse. In this review, we update our current understanding of SARS-CoV-2 infection via the nasal epithelium and the associated local immune response. Furthermore, we present considerations to how this interaction may influence the clinical course of COVID-19 and the systemic immune response, and lastly touch upon the potential for intranasal vaccination, intranasal antiviral therapies and immunomodulatory approaches

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Næsen kan være fokus for behandling af og profylakse mod COVID-19

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