Molecular epidemiology of the SARS-CoV-2 variant Omicron BA.2 sub-lineage in Denmark, 29 November 2021 to 2 January 2022

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  • Jannik Fonager, Statens Serum Institut
  • ,
  • Marc Bennedbæk, Statens Serum Institut
  • ,
  • Peter Bager, Statens Serum Institut
  • ,
  • Jan Wohlfahrt, Department of Epidemiology Research, Statens Serum Institut
  • ,
  • Kirsten Maren Ellegaard, Statens Serum Institut
  • ,
  • Anna Cäcilia Ingham, Statens Serum Institut
  • ,
  • Sofie Marie Edslev, Statens Serum Institut
  • ,
  • Marc Stegger, Statens Serum Institut
  • ,
  • Raphael Niklaus Sieber, Statens Serum Institut
  • ,
  • Ria Lassauniere, Statens Serum Institut
  • ,
  • Anders Fomsgaard, Statens Serum Institut
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  • Troels Lillebaek, Københavns Universitet, Statens Serum Institut
  • ,
  • Christina Wiid Svarrer, Statens Serum Institut
  • ,
  • Frederik Trier Møller, Statens Serum Institut
  • ,
  • Camilla Holten Møller
  • Rebecca Legarth, Statens Serum Institut
  • ,
  • Thomas Vognbjerg Sydenham, Syddansk Universitet
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  • Kat Steinke, Syddansk Universitet
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  • Sarah Juel Paulsen, Københavns Universitet
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  • José Alfredo Samaniego Castruita, Københavns Universitet
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  • Uffe Vest Schneider, Københavns Universitet
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  • Christian Højte Schouw, Sjællands Universitetshospital
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  • Xiaohui Chen Nielsen, Sjællands Universitetshospital
  • ,
  • Maria Overvad, Statens Serum Institut
  • ,
  • Rikke Thoft Nielsen, Department of Epidemiology Research & Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut
  • ,
  • Rasmus L. Marvig, Københavns Universitet
  • ,
  • Martin Schou Pedersen
  • Lene Nielsen, Københavns Universitet
  • ,
  • Line Lynge Nilsson, Københavns Universitet
  • ,
  • Jonas Bybjerg-Grauholm, Statens Serum Institut
  • ,
  • Irene Harder Tarpgaard
  • Tine Snejbjerg Ebsen
  • ,
  • Janni Uyen Hoa Lam, Statens Serum Institut
  • ,
  • Vithiagaran Gunalan, Statens Serum Institut
  • ,
  • Morten Rasmussen, Virus Research and Development Laboratory, Statens Serum Institut

Following emergence of the SARS-CoV-2 variant Omicron in November 2021, the dominant BA.1 sub-lineage was replaced by the BA.2 sub-lineage in Denmark. We analysed the first 2,623 BA.2 cases from 29 November 2021 to 2 January 2022. No epidemiological or clinical differences were found between individuals infected with BA.1 versus BA.2. Phylogenetic analyses showed a geographic east-to-west transmission of BA.2 from the Capital Region with clusters expanding after the Christmas holidays. Mutational analysis shows distinct differences between BA.1 and BA.2.

OriginalsprogEngelsk
TidsskriftEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Vol/bind27
Nummer10
ISSN1025-496X
DOI
StatusUdgivet - mar. 2022

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