Mitochondrial helicases and mitochondrial genome maintenance

Maria Diget Aamann, Nadja C de Souza-Pinto, Tomasz Kulikowicz, Tinna V Stevnsner, Vilhelm A Bohr

    Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisReviewForskningpeer review

    Abstract

    Helicases are essential enzymes that utilize the energy of nucleotide hydrolysis to drive unwinding of nucleic acid duplexes. Helicases play roles in all aspects of DNA metabolism including DNA repair, DNA replication and transcription. The subcellular locations and functions of several helicases have been studied in detail; however, the roles of specific helicases in mitochondrial biology remain poorly characterized. This review presents important recent advances in identifying and characterizing mitochondrial helicases, some of which also operate in the nucleus.
    OriginalsprogEngelsk
    TidsskriftMechanisms of Ageing and Development
    Vol/bind131
    Nummer7-8
    Sider (fra-til)503-10
    Antal sider8
    ISSN0047-6374
    DOI
    StatusUdgivet - 2010

    Fingeraftryk

    Dyk ned i forskningsemnerne om 'Mitochondrial helicases and mitochondrial genome maintenance'. Sammen danner de et unikt fingeraftryk.

    Citationsformater