Minimal Important Change for the 9-step Stair Climb Test in patients with knee osteoarthritis

Julie Pajaniaye*, Eric Cheret, Cecilie Langvad, Pætur Mikal Holm, Søren T Skou, Josefine Beck Larsen, Inger Mechlenburg

*Corresponding author af dette arbejde

Publikation: KonferencebidragKonferenceabstrakt til konferenceForskningpeer review


Background: Stair climb tests (SCT) evaluate stair negotiation and are part of the core recommendations for evaluating treatment effects on performance-based function in individuals with knee osteoarthritis (KOA). While no specific SCT is recommended, the 9-step SCT is commonly used. Minimal Important Change (MIC) is described as a measure of interpretability and is being defined as the minimum within-person change between repeated measurements that a patient would both perceive as a change and ascribe as important. The MIC of the 9-step SCT for patients with KOA has not yet been established.
Aim: The aim of this prospective cohort study was to estimate the MIC for the 9-step SCT for patients with KOA. Secondly, to assess the proportion of patients obtaining MIC, i.e. being responders to a 12-week exercise program, and to assess whether being a responder was associated with experiencing an important change.
Materials and methods: Data from a randomized controlled trial conducted from July 2017 to October 2018 at Næstved Hospital was used. Patients with KOA underwent a 12-week exercise intervention consisting of neuromuscular exercises with/without strength training. SCT data was collected at baseline and at 12-week follow-up. Patients’ self-reported experience of change of their knee problem was measured using the 7-point anchor question Global Perceived Effect Score (GPE) at follow-up. Perceived change was scored from “Better, an important improvement” to “Worse, an important worsening”. The MIC estimate for the SCT was calculated using logistic regression with predictive modeling. Results: 72 participants (54% women; mean age 65.5 years) had complete data. MIC value (95% CI) for improvement was 2.3 (–1.2; 7.3) seconds for the 9-step SCT. 29 of 72 participants (40%) in the trial were responders and there was a statistically significant association between being a responder and experiencing an important change (GPE scores 6 and 7).
Interpretation/Conclusion: The MIC value of 2.3 seconds for the 9-step SCT for patients with KOA corresponds to minimal improvements that the average patient finds important. The estimated MIC value should be confirmed in larger cohorts to establish a narrower confidence interval.
Publikationsdato15 nov. 2023
StatusUdgivet - 15 nov. 2023
BegivenhedDanish Orthopaedic Society Congress - Copenhagen, Danmark
Varighed: 15 nov. 202317 nov. 2023


KonferenceDanish Orthopaedic Society Congress