M-ficolin concentrations in cord blood are related to circulating phagocytes and to early-onset sepsis

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Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

DOI

https://doi.org/10.1038/pr.2011.71

Luregn J Schlapbach
Troels Rønn Kjær
Steffen Thiel
Maika Mattmann
Mathias Nelle
Bendicht P Wagner
Roland A Ammann
Christoph Aebi
Jens C Jensenius

The pattern-recognition molecule M-ficolin is synthesized by monocytes and neutrophils. M-ficolin activates the complement system in a manner similar to mannan-binding lectin (MBL), but little is known about its role in host defense. Neonates are highly vulnerable to bacterial sepsis, in particular, due to their decreased phagocytic function.

Originalsprog	Engelsk
Tidsskrift	Pediatric Research
Vol/bind	71
Nummer	4 Pt 1
Sider (fra-til)	368-74
Antal sider	7
ISSN	0031-3998
DOI	https://doi.org/10.1038/pr.2011.71
Status	Udgivet - 2012

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M-ficolin concentrations in cord blood are related to circulating phagocytes and to early-onset sepsis

DOI