Metabolite profiling of Solanum tuberosum reveals a differential response to Phytophthora infestans dependent on host resistance and pathogen isolate

TY - JOUR

T1 - Metabolite profiling of Solanum tuberosum reveals a differential response to Phytophthora infestans dependent on host resistance and pathogen isolate

AU - Abuley, Isaac Kwesi

AU - Pedersen, Hans Albert

AU - Stevens-Lekfeldt, Jonas Duus

AU - Fomsgaard, Inge S.

AU - Ravnskov, Sabine

PY - 2023/6

Y1 - 2023/6

N2 - The genetic basis of the resistance of potatoes to Phytophthora infestans is well-studied. Plant resistance to P. infestans is genetically controlled, and secondary metabolites play a role, but the metabolites themselves (e.g., phenylpropanoids) are poorly understood. This study aimed to characterize the effects of two P. infestans isolates and host resistance on secondary metabolite expression in potato plants. To do this, the phenylpropanoid pathway, chlorogenic acid, flavonoids, salicylic acid and jasmonic acid elicitors were characterized. The late blight-susceptible potato cultivar (Jutlandia) responded to both isolates with changes in the levels of compounds in the early phenylpropanoid pathway, whereas the response of the resistant cultivar (Toluca) occurred later in the pathway and was more marked in the case of the A2 mating-type isolate. The results reveal important differences in the role of secondary metabolism in resistance to P. infestans and suggest that different phenylpropanoids are affected depending on the isolate and the host's susceptibility to P. infestans.

AB - The genetic basis of the resistance of potatoes to Phytophthora infestans is well-studied. Plant resistance to P. infestans is genetically controlled, and secondary metabolites play a role, but the metabolites themselves (e.g., phenylpropanoids) are poorly understood. This study aimed to characterize the effects of two P. infestans isolates and host resistance on secondary metabolite expression in potato plants. To do this, the phenylpropanoid pathway, chlorogenic acid, flavonoids, salicylic acid and jasmonic acid elicitors were characterized. The late blight-susceptible potato cultivar (Jutlandia) responded to both isolates with changes in the levels of compounds in the early phenylpropanoid pathway, whereas the response of the resistant cultivar (Toluca) occurred later in the pathway and was more marked in the case of the A2 mating-type isolate. The results reveal important differences in the role of secondary metabolism in resistance to P. infestans and suggest that different phenylpropanoids are affected depending on the isolate and the host's susceptibility to P. infestans.

KW - late blight

KW - phenylpropanoid pathway

KW - secondary metabolites

KW - Solanum tuberosum

U2 - 10.1111/ppa.13714

DO - 10.1111/ppa.13714

M3 - Journal article

SN - 0032-0862

VL - 72

SP - 924

EP - 932

JO - Plant Pathology

JF - Plant Pathology

IS - 5

M1 - 13714

ER -