Mannan-binding lectin in diabetic kidney disease: the impact of mouse genetics in a type 1 diabetes model

Jakob Appel Østergaard; Mette Bjerre; Satish Posettihalli RamachandraRao; Anoop Kumar Sharma; Jens Randel Nyengaard; Troels Krarup Hansen; Steffen Thiel; Allan Flyvbjerg

doi:10.1155/2012/678381

Mannan-binding lectin in diabetic kidney disease: the impact of mouse genetics in a type 1 diabetes model

Jakob Appel Østergaard, Mette Bjerre, Satish Posettihalli RamachandraRao, Anoop Kumar Sharma, Jens Randel Nyengaard, Troels Krarup Hansen, Steffen Thiel, Allan Flyvbjerg

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

Abstract

BACKGROUND. Mannan-binding lectin (MBL) is involved in the development of diabetic nephropathy. MBL is a part of the innate immune system where it can activate the complement system. Serum MBL level predicts later renal impairment in diabetes patients. Direct involvement of MBL in the development of diabetic kidney disease is observed in one animal strain. However, this involvement may differ among the animal strains. We thus examined the impact of the genetic background on the role of MBL in diabetic nephropathy.

Originalsprog	Engelsk
Tidsskrift	Experimental Diabetes Research
Vol/bind	2012
Sider (fra-til)	678381
ISSN	1687-5214
DOI	https://doi.org/10.1155/2012/678381
Status	Udgivet - 2012

Adgang til dokumentet

10.1155/2012/678381

Citationsformater

@article{275a632038b04276af19d8670acd1d55,

title = "Mannan-binding lectin in diabetic kidney disease: the impact of mouse genetics in a type 1 diabetes model",

abstract = "BACKGROUND. Mannan-binding lectin (MBL) is involved in the development of diabetic nephropathy. MBL is a part of the innate immune system where it can activate the complement system. Serum MBL level predicts later renal impairment in diabetes patients. Direct involvement of MBL in the development of diabetic kidney disease is observed in one animal strain. However, this involvement may differ among the animal strains. We thus examined the impact of the genetic background on the role of MBL in diabetic nephropathy.",

author = "{\O}stergaard, {Jakob Appel} and Mette Bjerre and RamachandraRao, {Satish Posettihalli} and Sharma, {Anoop Kumar} and Nyengaard, {Jens Randel} and Hansen, {Troels Krarup} and Steffen Thiel and Allan Flyvbjerg",

year = "2012",

doi = "10.1155/2012/678381",

language = "English",

volume = "2012",

pages = "678381",

journal = "Experimental Diabetes Research",

issn = "1687-5214",

publisher = "Hindawi Publishing Corporation",

}

Mannan-binding lectin in diabetic kidney disease: the impact of mouse genetics in a type 1 diabetes model. / Østergaard, Jakob Appel ; Bjerre, Mette; RamachandraRao, Satish Posettihalli et al.
I: Experimental Diabetes Research, Bind 2012, 2012, s. 678381.

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avis › Tidsskriftartikel › Forskning › peer review

TY - JOUR

T1 - Mannan-binding lectin in diabetic kidney disease

T2 - the impact of mouse genetics in a type 1 diabetes model

AU - Østergaard, Jakob Appel

AU - Bjerre, Mette

AU - RamachandraRao, Satish Posettihalli

AU - Sharma, Anoop Kumar

AU - Nyengaard, Jens Randel

AU - Hansen, Troels Krarup

AU - Thiel, Steffen

AU - Flyvbjerg, Allan

PY - 2012

Y1 - 2012

N2 - BACKGROUND. Mannan-binding lectin (MBL) is involved in the development of diabetic nephropathy. MBL is a part of the innate immune system where it can activate the complement system. Serum MBL level predicts later renal impairment in diabetes patients. Direct involvement of MBL in the development of diabetic kidney disease is observed in one animal strain. However, this involvement may differ among the animal strains. We thus examined the impact of the genetic background on the role of MBL in diabetic nephropathy.

AB - BACKGROUND. Mannan-binding lectin (MBL) is involved in the development of diabetic nephropathy. MBL is a part of the innate immune system where it can activate the complement system. Serum MBL level predicts later renal impairment in diabetes patients. Direct involvement of MBL in the development of diabetic kidney disease is observed in one animal strain. However, this involvement may differ among the animal strains. We thus examined the impact of the genetic background on the role of MBL in diabetic nephropathy.

U2 - 10.1155/2012/678381

DO - 10.1155/2012/678381

M3 - Journal article

C2 - 22645604

SN - 1687-5214

VL - 2012

SP - 678381

JO - Experimental Diabetes Research

JF - Experimental Diabetes Research

ER -

Mannan-binding lectin in diabetic kidney disease: the impact of mouse genetics in a type 1 diabetes model

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater