Long-term follow-up of patients with Contained Annulus Ruptures after TAVI: the EuropeaN COntained RupturE (ENCORE) registry

Publikation: Bidrag til tidsskrift/Konferencebidrag i tidsskrift /Bidrag til avisTidsskriftartikelForskningpeer review


  • Philipp Breitbart, University Heart Center Freiburg
  • ,
  • Jan Minners, University Heart Center Freiburg
  • ,
  • Gregor Pache, University of Freiburg
  • ,
  • Nicolaj Christopher Hansson
  • Bjarne Linde Nørgaard
  • Ole De Backer, Rigshospitalet
  • ,
  • Lars Søndergaard, Rigshospitalet
  • ,
  • Osama Alsanjari, Brighton and Sussex University Hospitals, Brighton
  • ,
  • David Hildick-Smith, Brighton and Sussex University Hospitals, Brighton
  • ,
  • Mohamed Abdel-Wahab, Heart Center Leipzig, University Hospital, Germany
  • ,
  • Stephanie Löbig, Robert-Bosch-Medical Center Stuttgart
  • ,
  • Franz-Josef Neumann, University Heart Center Freiburg
  • ,
  • Philipp Ruile, University Heart Center Freiburg

AIMS: The purpose of this registry was to determine the long-term outcomes in patients with asymptomatic contained annulus rupture (CR) as a rare complication of transcatheter aortic valve implantation (TAVI).

METHODS AND RESULTS: The ENCORE registry is a multicentre registry (six centres across Europe) of patients with CR diagnosed on post-TAVI computed tomography angiography (CTA) or transoesophageal echocardiography (TEE). A total of 21 patients (mean age 81.9±4.1 years, 81% balloon-expandable TAVI prostheses) were diagnosed with CR (mean size of lesions was 15.3±6.9 × 8.5±3.3 × 8.5±2.3 mm). Seventeen were diagnosed among a total of 1,602 consecutive routine post-TAVI CTA (incidence 1.1%), two in TEE and two in post-TAVI CTA (each conducted due to suspicion of peri-interventional complications). During a mean follow-up of 2.3±1.7 years (cumulative 48.6 patient-years), nine patients (43%) died from non-cardiac causes. None of the patients exhibited symptoms or underwent interventional treatment related to the CR; no sudden cardiac death occurred. A follow-up CTA, performed in eleven patients 240±176 days post TAVI, revealed stable CR findings in seven, regression in one, and remission in three patients.

CONCLUSIONS: The results of our international multicentre registry demonstrate favourable long-term outcomes of CR after TAVI supporting a watch-and-wait strategy in these patients.

Sider (fra-til)83-88
Antal sider6
StatusUdgivet - maj 2020

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